Reactome | KIF24 [cytosol]

KIF24 [cytosol]

Stable Identifier

R-MMU-5626651

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

Q6NWW5

Locations in the PathwayBrowser

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Organelle biogenesis and maintenance (Mus musculus)

- Cilium Assembly (Mus musculus)
  - Anchoring of the basal body to the plasma membrane (Mus musculus)
    - C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole (Mus musculus)
      - Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        KIF24 [cytosol] (Mus musculus)
      - mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        KIF24 [cytosol] (Mus musculus)
    - C2CD3 binds the mother centriole (Mus musculus)
      - mother centriole [cytosol] (Mus musculus)
        
        KIF24 [cytosol] (Mus musculus)
      - mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        KIF24 [cytosol] (Mus musculus)
    - CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Mus musculus)
      - basal body:transition zone proteins [cytosol] (Mus musculus)
        
        basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        KIF24 [cytosol] (Mus musculus)
      - basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Mus musculus)
        
        basal body:transition zone proteins [cytosol] (Mus musculus)
        
        basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        KIF24 [cytosol] (Mus musculus)
    - CP110 and CEP97 dissociate from the centriole (Mus musculus)
      - basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        KIF24 [cytosol] (Mus musculus)
      - centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        KIF24 [cytosol] (Mus musculus)
    - MARK4 binds ODF2 in the centriole (Mus musculus)
      - Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        KIF24 [cytosol] (Mus musculus)
      - centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        KIF24 [cytosol] (Mus musculus)
    - RAB3IP stimulates nucleotide exchange on RAB8A (Mus musculus)
      - basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Mus musculus)
        
        basal body:transition zone proteins [cytosol] (Mus musculus)
        
        basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        KIF24 [cytosol] (Mus musculus)
    - Recruitment of transition zone proteins (Mus musculus)
      - basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        KIF24 [cytosol] (Mus musculus)
      - basal body:transition zone proteins [cytosol] (Mus musculus)
        
        basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        KIF24 [cytosol] (Mus musculus)
    - The distal appendage proteins recruit TTBK2 (Mus musculus)
      - Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        KIF24 [cytosol] (Mus musculus)
      - Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        KIF24 [cytosol] (Mus musculus)

External Reference Information

External Reference

UniProt:Q6NWW5

Reference Genes

BioGPS Gene:109242

ENSEMBL:ENSMUSG00000028438

ENSEMBL:ENSMUSG00000028438.17

KEGG Gene (Mus musculus):109242

Monarch:109242

NCBI Gene:109242

UCSC:Q6NWW5

Reference Transcript

Other Identifiers

10512236

105432_at

109242

132785_f_at

1457074_at

17424219

4314427

4438238

4446203

4497718

4501616

4652278

4662912

4663470

4678313

4709187

4760689

4832123

4880319

4944778

5013841

5033004

5111346

5135468

5157716

5356857

5454899

A_52_P220858

A_55_P2056630

A_66_P138930

GO:0000166

GO:0003774

GO:0003777

GO:0005515

GO:0005524

GO:0005737

GO:0005813

GO:0005814

GO:0005815

GO:0005856

GO:0005874

GO:0007010

GO:0007018

GO:0007019

GO:0008017

GO:0008092

GO:0030030

GO:0032991

GO:0042802

GO:0043226

GO:0044782

GO:0060271

GO:0140657

GO:1902018

ILMN_1246973

ILMN_2498470

ILMN_2936496

mMC013868

Participates

as a component of

Inferred From

KIF24 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_006537612.1, XP_011248205.1, NP_077203.2

Ensembl

ENSMUSP00000030148, ENSMUSG00000028438, ENSMUST00000030148, ENSMUST00000108055, ENSMUSP00000103690

PRO

Q6NWW5

MGI

1918345

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