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Rora, Ep300 bind Cpt1a gene
Stable Identifier
R-MMU-5663266
Type
Reaction [binding]
Species
Mus musculus
Compartment
nucleoplasm
ReviewStatus
5/5
General
SBML
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Level 2
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Rora binds the promoter of the Cpt1a gene and, together with coactivators Ep300 and PGC-1alpha, enhances transcription.
Literature References
PubMed ID
Title
Journal
Year
15199055
RORalpha regulates the expression of genes involved in lipid homeostasis in skeletal muscle cells: caveolin-3 and CPT-1 are direct targets of ROR
Parton, RG
,
Nixon, SJ
,
Lau, P
,
Muscat, GE
J Biol Chem
2004
Participants
Input
Cpt1a gene [nucleoplasm]
(Mus musculus)
Ep300 [nucleoplasm]
(Mus musculus)
Rora [nucleoplasm]
(Mus musculus)
Output
Rora:Ep300:Cpt1a gene [nucleoplasm]
(Mus musculus)
Orthologous Events
RORA, EP300 bind CPT1A gene (Homo sapiens)
Authored
May, B (2015-01-16)
Reviewed
Delaunay, F (2012-01-28)
Created
May, B (2015-01-17)
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