Rora, Ep300, Ppargc1a bind Nr1d1 gene

Stable Identifier
R-MMU-5663294
Type
Reaction [binding]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Rora, Ep300, Ppargc1a bind Nr1d1 gene

Rora binds the RRE DNA element and recruits the coactivators Pgc-1alpha (Ppargc1a) and p300 (Ep300, a histone acetyltransferase). Rora binds the promoter of the Nr1d1 gene and enhances transcription.

Literature References
PubMed ID Title Journal Year
18441015 The orphan nuclear receptor, RORalpha, regulates gene expression that controls lipid metabolism: staggerer (SG/SG) mice are resistant to diet-induced obesity

Lau, P, Fitzsimmons, RL, Raichur, S, Wang, SC, Lechtken, A, Muscat, GE

J Biol Chem 2008
Participants
Orthologous Events
Authored
Reviewed
Created
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