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phospho-Ksr1 [cytosol]
Stable Identifier
R-MMU-5672654
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
p-S311,S406 KSR1, Q61097
Locations in the PathwayBrowser
Expand all
Signal Transduction (Mus musculus)
MAPK family signaling cascades (Mus musculus)
MAPK1/MAPK3 signaling (Mus musculus)
RAF/MAP kinase cascade (Mus musculus)
RAF activation (Mus musculus)
MARK3 phosphorylates KSR1 (Mus musculus)
p-S311,S406 KSR1:MARK3 [cytosol] (Mus musculus)
phospho-Ksr1 [cytosol] (Mus musculus)
PP2A dephosphorylates KSR1 (Mus musculus)
p-S311,S406 KSR1:MARK3:YWHAB dimer [cytosol] (Mus musculus)
p-S311,S406 KSR1:MARK3 [cytosol] (Mus musculus)
phospho-Ksr1 [cytosol] (Mus musculus)
p-S311,S406 KSR1:MARK3 binds YWHAB dimer (Mus musculus)
p-S311,S406 KSR1:MARK3 [cytosol] (Mus musculus)
phospho-Ksr1 [cytosol] (Mus musculus)
p-S311,S406 KSR1:MARK3:YWHAB dimer [cytosol] (Mus musculus)
p-S311,S406 KSR1:MARK3 [cytosol] (Mus musculus)
phospho-Ksr1 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:Q61097
Gene Names
Ksr1
Reference Genes
BioGPS Gene:16706 Ksr1
ENSEMBL:ENSMUSG00000018334
KEGG Gene (Mus musculus):16706 Ksr1
Monarch:16706 Ksr1
NCBI Gene:16706 Ksr1
UCSC:Q61097 Ksr1
Reference Transcript
RefSeq:NM_013571.3 Ksr1
RefSeq:NM_001348207.1 Ksr1
RefSeq:XM_006532335.3 Ksr1
Other Identifiers
10388914
117128_at
1419823_s_at
1450114_at
16706
17266534
4353954
4384997
4389876
4482449
4519878
4585955
4680703
4688210
4703865
4838946
4998697
5027654
5031293
5039608
5058447
5167029
5271013
5287882
5326132
5351235
5404598
5443883
5459002
5557908
5566794
5578492
5614283
92764_at
92765_s_at
A_52_P114414
A_52_P666855
A_55_P1973233
A_55_P1973238
GE36674
GO:0000166
GO:0000185
GO:0003674
GO:0004672
GO:0004674
GO:0005078
GO:0005515
GO:0005524
GO:0005575
GO:0005622
GO:0005737
GO:0005783
GO:0005789
GO:0005886
GO:0006464
GO:0006468
GO:0007165
GO:0007265
GO:0008022
GO:0008150
GO:0008283
GO:0016020
GO:0016301
GO:0016310
GO:0016740
GO:0019899
GO:0019901
GO:0019933
GO:0030674
GO:0031434
GO:0032587
GO:0032991
GO:0035556
GO:0042127
GO:0042995
GO:0043167
GO:0043226
GO:0043405
GO:0043410
GO:0046872
GO:0051087
GO:0051879
GO:0071889
ILMN_1254652
ILMN_2849036
U43585_s_at
mMC002142
Participant Of
hasComponent
p-S311,S406 KSR1:MARK3 [cytosol]
Other forms of this molecule
Ksr1 [cytosol]
phospho-Ksr1 [cytosol]
phospho-Ksr1 [plasma membrane]
phospho-Ksr1 [cytosol]
Inferred From
p-S311,S406 KSR1 [cytosol] (Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 311 (in Homo sapiens)
Coordinate
311
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 406 (in Homo sapiens)
Coordinate
406
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
XP_006532398.1
,
NP_001335136.1
,
NP_038599.1
IntEnz
2.7.11.1
Ensembl
ENSMUST00000018478
,
ENSMUSP00000018478
,
ENSMUSG00000018334
PRO
Q61097
MGI
105051
PDB
1KBF
,
1KBE
,
2LPE
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P31946 YWHAB
1
YWHAB [cytosol]
(R-HSA-48888)
0.632
3
UniProt:P63101 Ywhaz
3
Ywhaz [nucleoplasm]
(R-MMU-450469)
Ywhaz [cytosol]
(R-MMU-206099)
14-3-3zeta [cytosol]
(R-MMU-206177)
0.547
2
UniProt:Q02750 MAP2K1
27
MAP2K1(2-8) [cytosol]
(R-HSA-5211342)
MAP2K1(9-393) [cytosol]
(R-HSA-5211353)
MAP2K1 F53S [cytosol]
(R-HSA-9652034)
MAP2K1 D67N [cytosol]
(R-HSA-9652016)
MAP2K1 Q56P [cytosol]
(R-HSA-9652064)
MAP2K1 E203K [cytosol]
(R-HSA-9652023)
MAP2K1 V60E [cytosol]
(R-HSA-9652067)
MAP2K1 P124S [cytosol]
(R-HSA-9652062)
MAP2K1 Y130C [cytosol]
(R-HSA-9652101)
MAP2K1 C121S [cytosol]
(R-HSA-9652013)
MAP2K1 G128V [cytosol]
(R-HSA-9652047)
MAP2K1 F53L [cytosol]
(R-HSA-9652031)
MAP2K1 K57N [cytosol]
(R-HSA-9652050)
MAP2K1 K57T [cytosol]
(R-HSA-9652052)
MAP2K1 F53V [cytosol]
(R-HSA-9652038)
MAP2K1 D67Y [cytosol]
(R-HSA-9652019)
MAP2K1 G128D [cytosol]
(R-HSA-9652043)
MAP2K1 P124L [cytosol]
(R-HSA-9652056)
MAP2K1 F53Y [cytosol]
(R-HSA-9652041)
MAP2K1 E44_E57del [cytosol]
(R-HSA-9652026)
MAP2K1 P124Q [cytosol]
(R-HSA-9652058)
MAP2K1 F53C [cytosol]
(R-HSA-9652028)
p-S,218, S222,T292 MAP2K1 [cytosol]
(R-HSA-5674490)
MAP2K1 [cytosol]
(R-HSA-59502)
p-T286,T292-MAP2K1 [cytosol]
(R-HSA-112374)
p-S218,S222,T286,T292-MAP2K1 [cytosol]
(R-HSA-112339)
p-S218,S222-MAP2K1 [cytosol]
(R-HSA-109837)
0.508
2
UniProt:P36507 MAP2K2
12
MAP2K2(11-400) [cytosol]
(R-HSA-5211337)
MAP2K2(1-10) [cytosol]
(R-HSA-5211334)
MAP2K2 C125S [cytosol]
(R-HSA-9652070)
MAP2K2 P128Q [cytosol]
(R-HSA-9652082)
MAP2K2 V35M [cytosol]
(R-HSA-9652086)
p-S,T-MAP2K2 [cytosol]
(R-HSA-109848)
p-S222,S226-MAP2K2 [cytosol]
(R-HSA-169292)
MAP2K2 [cytosol]
(R-HSA-59504)
MAP2K2 N126D [cytosol]
(R-HSA-9652079)
MAP2K2 L46F [cytosol]
(R-HSA-9652076)
MAP2K2 F57C [cytosol]
(R-HSA-9652073)
MAP2K2 Y134C [cytosol]
(R-HSA-9652089)
0.508
2
UniProt:P15056 BRAF
68
BRAF-MACF1fusion [cytosol]
(R-HSA-6802402)
p-S,T-BRAF [cytosol]
(R-HSA-169856)
p-BRAF-MACF1 fusion [cytosol]
(R-HSA-6802536)
BRAF [cytosol]
(R-HSA-167224)
BRAF E501G [cytosol]
(R-HSA-9651132)
BRAF D594N [cytosol]
(R-HSA-6802299)
BRAF D638E [cytosol]
(R-HSA-9651125)
BRAF G596R [cytosol]
(R-HSA-6802385)
BRAF D594V [cytosol]
(R-HSA-6802305)
BRAF G596V [cytosol]
(R-HSA-9651138)
BRAF G466E [cytosol]
(R-HSA-6802374)
BRAF D594G [cytosol]
(R-HSA-6802295)
BRAF L505H [cytosol]
(R-HSA-9648845)
BRAF F595L [cytosol]
(R-HSA-6802316)
BRAF L597V [cytosol]
(R-HSA-6802397)
BRAF G464E [cytosol]
(R-HSA-6802369)
BRAF N581D [cytosol]
(R-HSA-9651152)
BRAF E586K [cytosol]
(R-HSA-6802308)
BRAF V600K [cytosol]
(R-HSA-6802502)
BRAF A246P [cytosol]
(R-HSA-9651123)
BRAF G469V [cytosol]
(R-HSA-9648620)
BRAF T244P [cytosol]
(R-HSA-9651165)
BRAF G469R [cytosol]
(R-HSA-9648621)
BRAF L597R [cytosol]
(R-HSA-9648617)
BRAF G469E [cytosol]
(R-HSA-9648618)
BRAF L597Q [cytosol]
(R-HSA-9648619)
BRAF G466A [cytosol]
(R-HSA-9648613)
BRAF G466V [cytosol]
(R-HSA-9648838)
BRAF N581S [cytosol]
(R-HSA-9648850)
BRAF G464V [cytosol]
(R-HSA-9648611)
p-BRAF L597V [plasma membrane]
(R-HSA-8936647)
p-BRAF L505H [plasma membrane]
(R-HSA-9648862)
p-BRAF G464E [plasma membrane]
(R-HSA-8936645)
p-BRAF F595L [plasma membrane]
(R-HSA-8936641)
p-BRAF A246P [plasma membrane]
(R-HSA-9651188)
p-BRAF E586K [plasma membrane]
(R-HSA-8936639)
p-BRAF N581D [plasma membrane]
(R-HSA-9651191)
p-BRAF V600K [plasma membrane]
(R-HSA-8936651)
p-BRAF G464V [plasma membrane]
(R-HSA-9648633)
p-BRAF T244P [plasma membrane]
(R-HSA-9651194)
p-BRAF G469E [plasma membrane]
(R-HSA-9648634)
p-BRAF G466V [plasma membrane]
(R-HSA-9648859)
p-BRAF G469V [plasma membrane]
(R-HSA-9648628)
p-BRAF G466A [plasma membrane]
(R-HSA-9648629)
p-BRAF L597Q [plasma membrane]
(R-HSA-9648630)
p-BRAF L597R [plasma membrane]
(R-HSA-9648631)
p-BRAF N581S [plasma membrane]
(R-HSA-9648866)
p-BRAF G469R [plasma membrane]
(R-HSA-9648627)
BRAF 599dupT [cytosol]
(R-HSA-6802281)
BRAF G534R [cytosol]
(R-HSA-9651134)
BRAF S467A [cytosol]
(R-HSA-9651161)
BRAF K601N [cytosol]
(R-HSA-9648857)
BRAF G469A [cytosol]
(R-HSA-6802381)
BRAF L485F [cytosol]
(R-HSA-9651147)
BRAF Q257R [cytosol]
(R-HSA-9651157)
BRAF K499E [cytosol]
(R-HSA-9651142)
BRAF V600E [cytosol]
(R-HSA-6802498)
BRAF K601E [cytosol]
(R-HSA-9648833)
BRAF V600E V169_M438del [cytosol]
(R-HSA-6802489)
BRAF V600E V47_D380del [cytosol]
(R-HSA-6802491)
BRAF V600E V47_M438del [cytosol]
(R-HSA-6802495)
V600E BRAF V169_D380del [cytosol]
(R-HSA-6802486)
p-S445,S729-BRAF [plasma membrane]
(R-HSA-8933622)
hyperphosphorylated BRAF [plasma membrane]
(R-HSA-5675199)
p-S365,S445,S729 BRAF [cytosol]
(R-HSA-5672667)
p-S445,T599,S602,S729 BRAF [plasma membrane]
(R-HSA-5672679)
p-S445,S729-BRAF [cytosol]
(R-HSA-5672673)
p-S445,T599,S602,S729 BRAF [cytosol]
(R-HSA-5672676)
0.499
3
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