Reactome | Trappc6a [cytosol]

Trappc6a [cytosol]

Stable Identifier

R-MMU-5685733

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

TRAPPC6A, Q78XR0

Locations in the PathwayBrowser

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Metabolism of proteins (Mus musculus)

- Post-translational protein modification (Mus musculus)
  - Asparagine N-linked glycosylation (Mus musculus)
    - Transport to the Golgi and subsequent modification (Mus musculus)
      - ER to Golgi Anterograde Transport (Mus musculus)
        
        COPII-mediated vesicle transport (Mus musculus)
        
        COPII coat binds TRAPPCII and RAB1:GDP (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc6a [cytosol] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc6a [cytosol] (Mus musculus)
        
        CSNK1D phosphorylates SEC23 (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc6a [cytosol] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc6a [cytosol] (Mus musculus)
        
        Nucleotide exchange on RAB1 (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc6a [cytosol] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc6a [cytosol] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc6a [cytosol] (Mus musculus)
        
        RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc6a [cytosol] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc6a [cytosol] (Mus musculus)

Vesicle-mediated transport (Mus musculus)

- Membrane Trafficking (Mus musculus)
  - ER to Golgi Anterograde Transport (Mus musculus)
    - COPII-mediated vesicle transport (Mus musculus)
      - COPII coat binds TRAPPCII and RAB1:GDP (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc6a [cytosol] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc6a [cytosol] (Mus musculus)
      - CSNK1D phosphorylates SEC23 (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc6a [cytosol] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc6a [cytosol] (Mus musculus)
      - Nucleotide exchange on RAB1 (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc6a [cytosol] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc6a [cytosol] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc6a [cytosol] (Mus musculus)
      - RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc6a [cytosol] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc6a [cytosol] (Mus musculus)
  - Rab regulation of trafficking (Mus musculus)
    - RAB GEFs exchange GTP for GDP on RABs (Mus musculus)
      - TRAPPC complexes exchange GTP for GDP on RAB1 (Mus musculus)
        
        TRAPPCs [cytosol] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc6a [cytosol] (Mus musculus)
        
        TRAPPCIII [cytosol] (Mus musculus)
        
        Trappc6a [cytosol] (Mus musculus)

External Reference Information

External Reference

UniProt:Q78XR0

Gene Names

Trappc6a

Reference Genes

BioGPS Gene:67091 Trappc6a

ENSEMBL:ENSMUSG00000002043

ENSEMBL:ENSMUSG00000002043.18 Trappc6a

KEGG Gene (Mus musculus):67091 Trappc6a

Monarch:67091 Trappc6a

NCBI Gene:67091 Trappc6a

UCSC:Q78XR0 Trappc6a

Reference Transcript

Other Identifiers

10550715

1417034_at

17474647

4394715

4735314

4844129

4853388

4985876

5014760

5225874

67091

A_51_P485683

A_55_P2106250

GO:0005737

GO:0005783

GO:0005794

GO:0005801

GO:0005802

GO:0006888

GO:0016192

GO:0030008

GO:0043087

GO:0043226

GO:0048193

GO:0048208

GO:0061024

GO:0065003

GO:0099022

GO:1990072

ILMN_2643057

mMC024310

Participates

as a component of

Inferred From

TRAPPC6A [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_080236.2, NP_001318110.1

Ensembl

ENSMUST00000108455, ENSMUSP00000002112, ENSMUSP00000104095, ENSMUSG00000002043, ENSMUST00000002112

PRO

Q78XR0

MGI

1914341

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