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About
What is Reactome ?
News
Team
Scientific Advisory Board
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Editorial Calendar
Release Calendar
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Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
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Table of Contents
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Histone H2A.x [nucleoplasm]
Stable Identifier
R-MMU-573313
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
nucleoplasm
Synonyms
H2afx, H2AX_MOUSE, H2afx
Locations in the PathwayBrowser
Expand all
Cell Cycle (Mus musculus)
Cell Cycle, Mitotic (Mus musculus)
M Phase (Mus musculus)
Mitotic Prophase (Mus musculus)
Condensation of Prophase Chromosomes (Mus musculus)
CDK1 phosphorylates condensin II subunit NCAPD3 (Mus musculus)
Condensin II:Nucleosome with H4K20me1 [nucleoplasm] (Mus musculus)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Phosphorylated Condensin II:Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
PLK1 binds phosphorylated condensin II complex (Mus musculus)
Phosphorylated Condensin II:Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
p-T210-PLK1:Phosphorylated Condensin II:Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
PLK1 hyperphosphorylates Condensin II complex (Mus musculus)
Hyperphosphorylated Condensin II:Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
p-T210-PLK1:Phosphorylated Condensin II:Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Chromosome Maintenance (Mus musculus)
Nucleosome assembly (Mus musculus)
Deposition of new CENPA-containing nucleosomes at the centromere (Mus musculus)
RSF complex binds the centromere (Mus musculus)
CCAN:DNA:CASC5:Centromeric nucleosome:RSF complex [nucleoplasm] (Mus musculus)
Centromeric Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
CCAN:DNA:CASC5:Mis18 complex:HJURP complex:CENPA nucleosome [nucleoplasm] (Mus musculus)
Centromeric Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Telomere Maintenance (Mus musculus)
Inhibition of DNA recombination at telomere (Mus musculus)
ATRX:DAXX binds to subtelomeric chromosomal regions (Mus musculus)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Telomere:Shelterin:Nucleosome:ATRX:DAXX [nucleoplasm] (Mus musculus)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Histone H3.3 deposition at telomere (Mus musculus)
Telomere:Shelterin:Nucleosome (H3F3A):ATRX:DAXX [nucleoplasm] (Mus musculus)
Telomere:Shelterin:Nucleosome (H3F3A) [nucleoplasm] (Mus musculus)
Nucleosome (H3F3A) [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Telomere:Shelterin:Nucleosome:ATRX:DAXX [nucleoplasm] (Mus musculus)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Cellular responses to stimuli (Mus musculus)
Cellular responses to stress (Mus musculus)
Cellular Senescence (Mus musculus)
DNA Damage/Telomere Stress Induced Senescence (Mus musculus)
Telomere shortening during replicative exhaustion (Mus musculus)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
DNA Repair (Mus musculus)
Base Excision Repair (Mus musculus)
Base-Excision Repair, AP Site Formation (Mus musculus)
Depurination (Mus musculus)
Cleavage of the damaged purine (Mus musculus)
NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA (Mus musculus)
NEIL3:AP-Telomeric DNA:Shelterin [nucleoplasm] (Mus musculus)
AP-Telomeric DNA:Shelterin [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
NEIL3:Gh-Telomeric DNA:Shelterin [nucleoplasm] (Mus musculus)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Recognition and association of DNA glycosylase with site containing an affected purine (Mus musculus)
NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA (Mus musculus)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
NEIL3:Gh-Telomeric DNA:Shelterin [nucleoplasm] (Mus musculus)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
DNA Double-Strand Break Repair (Mus musculus)
DNA Double Strand Break Response (Mus musculus)
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks (Mus musculus)
WICH phosphorylates H2AFX on Y142 (Mus musculus)
H2AFX-Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Gene expression (Transcription) (Mus musculus)
Epigenetic regulation of gene expression (Mus musculus)
Epigenetic regulation by WDR5-containing histone modifying complexes (Mus musculus)
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes (Mus musculus)
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes (Mus musculus)
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis (Mus musculus)
RXRA binds ligands (Mus musculus)
PPARG ligands:PPARG:RXRA ligands:RXRA:Corepressors:adipogenesis genes:Nucleosomes [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:ACSL1 gene:nucleosomes [nucleoplasm] (Mus musculus)
ACSL1 gene:Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:ADIPOQ gene:nucleosomes [nucleoplasm] (Mus musculus)
ADIPOQ gene:Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:AGPAT2 gene:nucleosomes [nucleoplasm] (Mus musculus)
AGPAT2 gene:nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:ANGPTL4 gene:nucleosomes [nucleoplasm] (Mus musculus)
ANGPTL4 gene:Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:CD36 gene:nucleosomes [nucleoplasm] (Mus musculus)
CD36 gene:Nucleosomes [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:CEBPA gene:nucleosomes [nucleoplasm] (Mus musculus)
CEBPA gene:Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:CIDEC gene:nucleosomes [nucleoplasm] (Mus musculus)
CIDEC gene:nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:DGAT2 gene:nucleosomes [nucleoplasm] (Mus musculus)
DGAT2 gene:Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:FABP4 gene:nucleosomes [nucleoplasm] (Mus musculus)
FABP4 gene:Nucleosomes [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:LIPE gene:nucleosomes [nucleoplasm] (Mus musculus)
LIPE gene:Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:LPIN1 gene:nucleosomes [nucleoplasm] (Mus musculus)
LPIN1 gene:Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:LPL gene:nucleosomes [nucleoplasm] (Mus musculus)
LPL gene:Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:MGLL gene:nucleosomes [nucleoplasm] (Mus musculus)
MGLL gene:Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:PDK4 gene:nucleosomes [nucleoplasm] (Mus musculus)
PDK4 gene:Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:PEX11A gene:nucleosomes [nucleoplasm] (Mus musculus)
PEX11A gene:Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:PLIN1 gene:nucleosomes [nucleoplasm] (Mus musculus)
PLIN1 gene:Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:PLIN2 gene:nucleosomes [nucleoplasm] (Mus musculus)
PLIN2 gene:nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:PLIN4 gene:nucleosomes [nucleoplasm] (Mus musculus)
PLIN4 gene:Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:PNPLA2 gene:nucleosomes [nucleoplasm] (Mus musculus)
PNPLA2 gene:Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:PPARG gene:nucleosomes [nucleoplasm] (Mus musculus)
PPARG gene:Nucleosomes [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:SCD gene:nucleosomes [nucleoplasm] (Mus musculus)
SCD gene:Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound p-Y78,Y102-PPARG2:Ligand-bound RXRA:NCoR/SMRT:ACSS3 gene:nucleosomes [nucleoplasm] (Mus musculus)
p-Y78,Y102-PPARG2:RXRA:ACSS3 gene:nucleosomes [nucleoplasm] (Mus musculus)
ACSS3 gene:nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound p-Y78,Y102-PPARG2:Ligand-bound RXRA:NCoR/SMRT:ELOVL5 gene:nucleosomes [nucleoplasm] (Mus musculus)
p-Y78,Y102-PPARG2:RXRA:ELOVL5 gene:nucleosomes [nucleoplasm] (Mus musculus)
ELOVL5 gene:nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound p-Y78,Y102-PPARG2:Ligand-bound RXRA:NCoR/SMRT:GPAM gene:nucleosomes [nucleoplasm] (Mus musculus)
p-Y78,Y102-PPARG2:RXRA:GPAM gene:nucleosomes [nucleoplasm] (Mus musculus)
GPAM gene:nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound p-Y78,Y102-PPARG2:Ligand-bound RXRA:NCoR/SMRT:SCD5 gene:nucleosomes [nucleoplasm] (Mus musculus)
p-Y78,Y102-PPARG2:RXRA:SCD5 gene:nucleosomes [nucleoplasm] (Mus musculus)
SCD5 gene:nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound p-Y78,Y102-PPARG2:Ligand-bound RXRA:NCoR/SMRT:THRSP gene:nucleosomes [nucleoplasm] (Mus musculus)
p-Y78,Y102-PPARG2:RXRA:THRSP gene:nucleosomes [nucleoplasm] (Mus musculus)
THRSP gene:nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
PPARG ligands:PPARG:RXRA:Corepressors:adipogenesis genes:Nucleosomes [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:RXRA:NCoR/SMRT:ACSL1 gene:nucleosomes [nucleoplasm] (Mus musculus)
ACSL1 gene:Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:RXRA:NCoR/SMRT:ADIPOQ gene:nucleosomes [nucleoplasm] (Mus musculus)
ADIPOQ gene:Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:RXRA:NCoR/SMRT:AGPAT2 gene:nucleosomes [nucleoplasm] (Mus musculus)
AGPAT2 gene:nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:RXRA:NCoR/SMRT:ANGPTL4 gene:nucleosomes [nucleoplasm] (Mus musculus)
ANGPTL4 gene:Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:RXRA:NCoR/SMRT:CD36 gene:nucleosomes [nucleoplasm] (Mus musculus)
CD36 gene:Nucleosomes [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:RXRA:NCoR/SMRT:CEBPA gene:nucleosomes [nucleoplasm] (Mus musculus)
CEBPA gene:Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:RXRA:NCoR/SMRT:CIDEC gene:nucleosomes [nucleoplasm] (Mus musculus)
CIDEC gene:nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:RXRA:NCoR/SMRT:DGAT2 gene:nucleosomes [nucleoplasm] (Mus musculus)
DGAT2 gene:Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:RXRA:NCoR/SMRT:FABP4 gene:nucleosomes [nucleoplasm] (Mus musculus)
FABP4 gene:Nucleosomes [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:RXRA:NCoR/SMRT:LIPE gene:nucleosomes [nucleoplasm] (Mus musculus)
LIPE gene:Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:RXRA:NCoR/SMRT:LPIN1 gene:nucleosomes [nucleoplasm] (Mus musculus)
LPIN1 gene:Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:RXRA:NCoR/SMRT:LPL gene:nucleosomes [nucleoplasm] (Mus musculus)
LPL gene:Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:RXRA:NCoR/SMRT:MGLL gene:nucleosomes [nucleoplasm] (Mus musculus)
MGLL gene:Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:RXRA:NCoR/SMRT:PDK4 gene:nucleosomes [nucleoplasm] (Mus musculus)
PDK4 gene:Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:RXRA:NCoR/SMRT:PEX11A gene:nucleosomes [nucleoplasm] (Mus musculus)
PEX11A gene:Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:RXRA:NCoR/SMRT:PLIN1 gene:nucleosomes [nucleoplasm] (Mus musculus)
PLIN1 gene:Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:RXRA:NCoR/SMRT:PLIN2 gene:nucleosomes [nucleoplasm] (Mus musculus)
PLIN2 gene:nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:RXRA:NCoR/SMRT:PLIN4 gene:nucleosomes [nucleoplasm] (Mus musculus)
PLIN4 gene:Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:RXRA:NCoR/SMRT:PNPLA2 gene:nucleosomes [nucleoplasm] (Mus musculus)
PNPLA2 gene:Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:RXRA:NCoR/SMRT:PPARG gene:nucleosomes [nucleoplasm] (Mus musculus)
PPARG gene:Nucleosomes [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound PPARG:RXRA:NCoR/SMRT:SCD gene:nucleosomes [nucleoplasm] (Mus musculus)
SCD gene:Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound p-Y78,Y102-PPARG2:RXRA:NCoR/SMRT:ACSS3 gene:nucleosomes [nucleoplasm] (Mus musculus)
p-Y78,Y102-PPARG2:RXRA:ACSS3 gene:nucleosomes [nucleoplasm] (Mus musculus)
ACSS3 gene:nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound p-Y78,Y102-PPARG2:RXRA:NCoR/SMRT:ELOVL5 gene:nucleosomes [nucleoplasm] (Mus musculus)
p-Y78,Y102-PPARG2:RXRA:ELOVL5 gene:nucleosomes [nucleoplasm] (Mus musculus)
ELOVL5 gene:nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound p-Y78,Y102-PPARG2:RXRA:NCoR/SMRT:GPAM gene:nucleosomes [nucleoplasm] (Mus musculus)
p-Y78,Y102-PPARG2:RXRA:GPAM gene:nucleosomes [nucleoplasm] (Mus musculus)
GPAM gene:nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound p-Y78,Y102-PPARG2:RXRA:NCoR/SMRT:SCD5 gene:nucleosomes [nucleoplasm] (Mus musculus)
p-Y78,Y102-PPARG2:RXRA:SCD5 gene:nucleosomes [nucleoplasm] (Mus musculus)
SCD5 gene:nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Ligand-bound p-Y78,Y102-PPARG2:RXRA:NCoR/SMRT:THRSP gene:nucleosomes [nucleoplasm] (Mus musculus)
p-Y78,Y102-PPARG2:RXRA:THRSP gene:nucleosomes [nucleoplasm] (Mus musculus)
THRSP gene:nucleosome [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
PRC2 methylates histones and DNA (Mus musculus)
DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 (Mus musculus)
DNMT1,3A,3B:PRC2:Chromatin (5-mC, H3K27me3) [nucleoplasm] (Mus musculus)
PRC2:Chromatin (5-methylcytosine, H3K27me3) [nucleoplasm] (Mus musculus)
Chromatin with hemimethylC, H3K27me3 [nucleoplasm] (Mus musculus)
Nucleosome with H3K27me3 [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
DNMT1,3A,3B:PRC2:Chromatin [nucleoplasm] (Mus musculus)
PRC2 Core:Chromatin [nucleoplasm] (Mus musculus)
Chromatin [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
PRC2 recruits DNA methyltransferases (Mus musculus)
DNMT1,3A,3B:PRC2:Chromatin [nucleoplasm] (Mus musculus)
PRC2 Core:Chromatin [nucleoplasm] (Mus musculus)
Chromatin [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
PRC2 Core:Chromatin [nucleoplasm] (Mus musculus)
Chromatin [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
PRC2 trimethylates histone H3 at lysine-27 (Mus musculus)
PRC2:Chromatin (H3K27me3) [nucleoplasm] (Mus musculus)
Chromatin with trimethylated H3K27 [nucleoplasm] (Mus musculus)
Nucleosome with H3K27me3 [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
PRC2:Chromatin [nucleoplasm] (Mus musculus)
Chromatin [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Regulation of endogenous retroelements (Mus musculus)
Regulation of endogenous retroelements by KRAB-ZFP proteins (Mus musculus)
SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes (Mus musculus)
ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin [nucleoplasm] (Mus musculus)
KRAB-ZFP:retroelement chromatin [nucleoplasm] (Mus musculus)
Retroelement chromatin [nucleoplasm] (Mus musculus)
Nucleosome [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin with H3K9me3 [nucleoplasm] (Mus musculus)
KRAB-ZFP:retroelement chromatin with H3K9me3 [nucleoplasm] (Mus musculus)
Retroelement chromatin with H3K9me3 [nucleoplasm] (Mus musculus)
Nucleosome with H3K9me3 [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
RNA Polymerase II Transcription (Mus musculus)
Generic Transcription Pathway (Mus musculus)
Transcriptional regulation by RUNX1 (Mus musculus)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function (Mus musculus)
Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter (Mus musculus)
H3K4me2-Nucleosome:GP1BA gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Mus musculus)
Nucleosome with H3K4me2 [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
H3K4me3-Nucleosome:GP1BA gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Mus musculus)
Nucleosome with H3K4me3 [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter (Mus musculus)
H3K4me2-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Mus musculus)
Nucleosome with H3K4me2 [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
H3K4me3-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Mus musculus)
Nucleosome with H3K4me3 [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Mus musculus)
H3K4me2-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Mus musculus)
Nucleosome with H3K4me2 [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
H3K4me3-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Mus musculus)
Nucleosome with H3K4me3 [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter (Mus musculus)
H3K4me2-Nucleosome:THBS1 gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Mus musculus)
Nucleosome with H3K4me2 [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
H3K4me3-Nucleosome:THBS1 gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Mus musculus)
Nucleosome with H3K4me3 [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter (Mus musculus)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:GP1BA gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome with H3K4me2 and H3R2me2a [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:GP1BA gene:H3K4me2-Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome with H3K4me2 [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter (Mus musculus)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:ITGA2B gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome with H3K4me2 and H3R2me2a [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:ITGA2B gene:H3K4me2-Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome with H3K4me2 [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter (Mus musculus)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:MIR27A gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome with H3K4me2 and H3R2me2a [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:MIR27A gene:H3K4me2-Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome with H3K4me2 [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter (Mus musculus)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:THBS1 gene:H3K4me2-Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome with H3K4me2 [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:THBS1B gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Mus musculus)
Nucleosome with H3K4me2 and H3R2me2a [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A.x [nucleoplasm] (Mus musculus)
External Reference Information
External Reference
UniProt:P27661 H2afx
Gene Names
H2afx, H2a.x, H2ax, Hist5-2ax
Chain
initiator methionine:, chain:2-143
Reference Genes
BioGPS Gene:15270 H2afx
KEGG:mmu:15270 H2afx
Monarch:15270 H2afx
NCBI Gene:15270 H2afx
UCSC:P27661 H2afx
Reference Transcript
RefSeq:NM_010436.2 H2afx
Other Identifiers
10403955
10404026
10404045
10408072
10408085
10408094
10408111
10409220
10500324
10584710
1416746_at
15270
17516558
4317557
4377166
4571512
4598206
4670517
4728274
4755297
4925967
4959729
5036590
5078347
5134172
5144850
5246749
5293064
5523296
5549641
93019_at
GO:0000228
GO:0000724
GO:0000781
GO:0000785
GO:0000786
GO:0000794
GO:0001673
GO:0001741
GO:0003677
GO:0003684
GO:0005198
GO:0005515
GO:0005634
GO:0005654
GO:0005657
GO:0005694
GO:0005813
GO:0005815
GO:0006281
GO:0006310
GO:0006325
GO:0006974
GO:0007283
GO:0016607
GO:0019899
GO:0021987
GO:0022414
GO:0030527
GO:0031492
GO:0031507
GO:0035861
GO:0042393
GO:0043226
GO:0046982
GO:0048856
GO:0051321
GO:0060090
GO:0071480
GO:0090398
GO:0090734
GO:0140463
GO:1990166
ILMN_1235873
ILMN_2525581
ILMN_2525595
ILMN_2525605
ILMN_2907878
X58069_s_at
aa269806_s_at
mMC011909
Participates
as a component of
Nucleosome with H3.3 dimethylarginine-17, H2ax [nucleoplasm] (Mus musculus)
Nucleosome with H3.3 and H2ax [nucleoplasm] (Mus musculus)
Nucleosome with Histone H2A.x [nucleoplasm] (Mus musculus)
H2AFX-Nucleosome [nucleoplasm] (Mus musculus)
as an input of
Hira and Npm2 assemble H3.3-containing nucleosomes on paternal DNA (Mus musculus)
as a candidate of
Histone H2A [nucleoplasm] (Mus musculus)
Histone H2A [nucleoplasm] (Mus musculus)
Other forms of this molecule
phospho-H2ax [nucleoplasm]
phospho-H2ax [nucleoplasm]
p-S140-H2afx [nucleoplasm]
phospho-H2ax [nucleoplasm]
Inferred From
H2AFX [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_034566.1
ENSEMBL
ENSMUSP00000051432
,
ENSMUST00000052686
PRO
P27661
MGI
102688
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9Z0X1 AIFM1
0.556
3
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