Cbx3 (HP1gamma) Binds Histone H3 dimethylated at lysine-9

Stable Identifier
R-MMU-573393
Type
Reaction [binding]
Species
Mus musculus
Compartment
ReviewStatus
5/5
General
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Cbx3 (HP1gamma) Binds Histone H3 dimethylated at lysine-9
Histone H3 dimethylated at lysine-9 is bound by Heterochromatic Protein 1gamma (HP1gamma, Cbx3). In other regions of the genome, Cbx3 can be associated with repression of transcription, however dimethylated H3 lysine-9 and Cbx3 in the coding region of the rRNA gene is associated with expression (Yuan et al. 2007). Cbx3 in coding regions is associated with transcription elongation (Vakoc et al. 2005)
Literature References
PubMed ID Title Journal Year
17707230 Activation of RNA polymerase I transcription by cockayne syndrome group B protein and histone methyltransferase G9a

Zhou, Y, Grummt, I, Feng, W, Yuan, X, Imhof, A

Mol Cell 2007
16061184 Histone H3 lysine 9 methylation and HP1gamma are associated with transcription elongation through mammalian chromatin

Vakoc, CR, Olenchock, BA, Mandat, SA, Blobel, GA

Mol. Cell 2005
Participants
Orthologous Events
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