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Irs2 [cytosol]
Stable Identifier
R-MMU-57528
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
IRS2, P81122
Locations in the PathwayBrowser for interactor UniProt:Q13625-2 TP53BP2
Expand all
Signal Transduction (Mus musculus)
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Mus musculus)
IGF1R signaling cascade (Mus musculus)
IRS-related events triggered by IGF1R (Mus musculus)
IGF1,2:p-Y1161,1165,1166-IGF1R binds IRS2 (Mus musculus)
Irs2 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:P81122 Irs2
Gene Names
Irs2
Chain
chain:1-1321
Reference Genes
BioGPS Gene:384783 Irs2
KEGG:mmu:384783 Irs2
Monarch:384783 Irs2
NCBI Gene:384783 Irs2
UCSC:P81122 Irs2
Reference Transcript
RefSeq:NM_001081212.1 Irs2
Other Identifiers
10576971
1443969_at
17507374
384783
4585546
4739480
4798891
5043042
5411914
5531065
92205_at
A_66_P102260
GO:0002053
GO:0002903
GO:0005068
GO:0005158
GO:0005515
GO:0005737
GO:0005829
GO:0005886
GO:0007165
GO:0007420
GO:0008283
GO:0008284
GO:0008286
GO:0009749
GO:0010631
GO:0010634
GO:0010748
GO:0010907
GO:0016477
GO:0019901
GO:0019903
GO:0019904
GO:0030674
GO:0030879
GO:0030890
GO:0032000
GO:0032024
GO:0032869
GO:0033673
GO:0043548
GO:0044342
GO:0045725
GO:0046326
GO:0048856
GO:0048870
GO:0051897
GO:0060090
GO:0071333
GO:0071889
GO:0098772
GO:0141038
GO:1901653
GO:1904692
ILMN_3144164
Participates
as a member of
RET interactors [cytosol] (Mus musculus)
IRS1,2 [cytosol] (Mus musculus)
as a component of
EPOR:JAK2:LYN:IRS2 [plasma membrane] (Mus musculus)
p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2 [plasma membrane] (Mus musculus)
as an input of
IGF1,2:p-Y1161,1165,1166-IGF1R binds IRS2 (Mus musculus)
Other forms of this molecule
p-Irs2 [cytosol]
Irs2 [plasma membrane]
Phospho-IRS2 (by NTRK1) [cytosol]
Irs2 [cytosol]
phospho-Irs2 [cytosol]
phospho-Irs2 [plasma membrane]
Inferred From
IRS2 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001074681.1
ENSEMBL
ENSMUST00000040514
,
ENSMUSP00000038514
,
ENSMUSG00000038894
PRO
P81122
GlyGen
P81122
MGI
109334
PDB
3BU3
,
3BU5
,
3BU6
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P06213-1 INSR
0.655
8
UniProt:Q8CGK3
1
LONP1 [mitochondrial matrix]
(R-MMU-9838000)
0.508
2
UniProt:P09405
1
Ncl [nucleoplasm]
(R-MMU-6791213)
0.508
2
UniProt:Q8BHZ4 ZN592
0.508
2
UniProt:Q13625-2 TP53BP2
0.482
2
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