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Tcea1 [nucleoplasm]
Stable Identifier
R-MMU-65748
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
nucleoplasm
Synonyms
TCEA1, P10711
Locations in the PathwayBrowser
Expand all
DNA Repair (Mus musculus)
Nucleotide Excision Repair (Mus musculus)
Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Mus musculus)
Dual incision in TC-NER (Mus musculus)
3' incision by ERCC5 (XPG) in TC-NER (Mus musculus)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER (Mus musculus)
TC-NER incision complex [nucleoplasm] (Mus musculus)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Mus musculus)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER (Mus musculus)
TC-NER incision complex [nucleoplasm] (Mus musculus)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Mus musculus)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Mus musculus)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
DNA polymerases delta, epsilon or kappa bind the TC-NER site (Mus musculus)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
ERCC2-facilitated RNA Pol II backtracking in TC-NER (Mus musculus)
TC-NER pre-incision complex [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
ERCC3-facilitated RNA Pol II backtracking in TC-NER (Mus musculus)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
ERCC5 and RPA bind TC-NER site (Mus musculus)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Mus musculus)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
Formation of TC-NER Pre-Incision Complex (Mus musculus)
Assembly of the pre-incision complex in TC-NER (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300 [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
UVSSA:USP7 deubiquitinates ERCC6 (Mus musculus)
TC-NER pre-incision complex [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300 [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
Gap-filling DNA repair synthesis and ligation in TC-NER (Mus musculus)
Ligation of newly synthesized repair patch to incised DNA in TC-NER (Mus musculus)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
TC-NER post-incision complex:dsDNA with transcription bubble [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Mus musculus)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
Gene expression (Transcription) (Mus musculus)
RNA Polymerase II Transcription (Mus musculus)
Generic Transcription Pathway (Mus musculus)
Transcriptional Regulation by TP53 (Mus musculus)
TP53 Regulates Transcription of DNA Repair Genes (Mus musculus)
CCNK:CDK12 binds RNA Pol II at DNA repair genes (Mus musculus)
CCNK:CDK12:Elongation Complex at DNA Repair Genes [nucleoplasm] (Mus musculus)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
CDK12 phosphorylates RNA Pol II CTD at DNA repair genes (Mus musculus)
CCNK:CDK12:CDK12-Phosphorylated Elongation Complex at DNA repair genes [nucleoplasm] (Mus musculus)
CDK12-Phosphorylated Elongation Complex [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
CCNK:CDK12:Elongation Complex at DNA Repair Genes [nucleoplasm] (Mus musculus)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
RNA Polymerase II Pre-transcription Events (Mus musculus)
2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing (Mus musculus)
Paused processive elongation complex [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
Processive elongation complex [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest (Mus musculus)
Processive elongation complex [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
Abortive termination of elongation after arrest (Mus musculus)
Aborted elongation complex after arrest [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
Processive elongation complex [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
Elongating transcript encounters a lesion in the template (Mus musculus)
Processive elongation complex [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
Resumption of elongation after recovery from pausing (Mus musculus)
Paused processive elongation complex [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
Processive elongation complex [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
TFIIS-mediated recovery of elongation from arrest (Mus musculus)
Processive elongation complex [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
RNA Polymerase II Transcription Elongation (Mus musculus)
Addition of nucleotides leads to transcript elongation (Mus musculus)
Elongation complex [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
Processive elongation complex [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
Formation of RNA Pol II elongation complex (Mus musculus)
Recruitment of elongation factors to form elongation complex (Mus musculus)
Elongation complex [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
Pol II elongation complex moves on the template as transcript elongates (Mus musculus)
Elongation complex prior to separation [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
Processive elongation complex [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
Separation of elongating transcript from template (Mus musculus)
Elongation complex prior to separation [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
Elongation complex with separated and uncleaved transcript [nucleoplasm] (Mus musculus)
Tcea1 [nucleoplasm] (Mus musculus)
External Reference Information
External Reference
UniProt:P10711
Gene Names
Tcea1
Reference Genes
BioGPS Gene:21399 Tcea1
ENSEMBL:ENSMUSG00000033813
KEGG:mmu:21399 Tcea1
Monarch:21399 Tcea1
NCBI Gene:21399 Tcea1
UCSC:P10711 Tcea1
Reference Transcript
RefSeq:NM_001159751.1 Tcea1
RefSeq:NM_001159750.1 Tcea1
RefSeq:NM_011541.4 Tcea1
Other Identifiers
101527_at
101528_at
101529_g_at
10344633
10426301
1419257_at
1419258_at
17210869
21399
4305408
4383934
4384108
4446503
4574646
4603734
4697504
4769092
4804231
4921825
4936475
4984395
4986679
5045621
5133087
5135107
5152434
5233483
5292345
5330036
5391845
5463574
5476405
5497111
5592486
5599739
5609681
5615723
A_52_P417654
GE36176
GO:0003676
GO:0003677
GO:0005515
GO:0005634
GO:0005654
GO:0006351
GO:0006355
GO:0006368
GO:0008270
GO:0030154
GO:0030218
GO:0043226
GO:0045893
GO:0045944
ILMN_2661939
Msa.43200.0_s_at
m18209_s_at
mMC025926
Participates
as an output of
Elongating transcript encounters a lesion in the template (Mus musculus)
as a component of
Aborted elongation complex after arrest [nucleoplasm] (Mus musculus)
Paused processive elongation complex [nucleoplasm] (Mus musculus)
Elongation complex with separated and uncleaved transcript [nucleoplasm] (Mus musculus)
Elongation complex prior to separation [nucleoplasm] (Mus musculus)
Processive elongation complex [nucleoplasm] (Mus musculus)
Elongation complex [nucleoplasm] (Mus musculus)
TC-NER post-incision complex:dsDNA with transcription bubble [nucleoplasm] (Mus musculus)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Mus musculus)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Mus musculus)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Mus musculus)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Mus musculus)
TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Mus musculus)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Mus musculus)
TC-NER pre-incision complex [nucleoplasm] (Mus musculus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300 [nucleoplasm] (Mus musculus)
CDK12-Phosphorylated Elongation Complex [nucleoplasm] (Mus musculus)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Mus musculus)
as an input of
Recruitment of elongation factors to form elongation complex (Mus musculus)
Assembly of the pre-incision complex in TC-NER (Mus musculus)
Inferred From
TCEA1 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_035671.1
,
NP_001153222.1
,
NP_001153223.1
ENSEMBL
ENSMUST00000081551
,
ENSMUSP00000080266
,
ENSMUSG00000033813
PRO
P10711
MGI
1196624
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