Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
TRADD [cytosol]
Stable Identifier
R-MMU-66376
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
Q3U0V2
Locations in the PathwayBrowser for interactor UniProt:Q60855
Expand all
Signal Transduction (Mus musculus)
Death Receptor Signaling (Mus musculus)
TNF signaling (Mus musculus)
Regulation of TNFR1 signaling (Mus musculus)
TRAF1 binds TRAF2 within TNFR1 signaling complex (Mus musculus)
TRADD [cytosol] (Mus musculus)
TNF:TNFR1 binds TRADD, TRAF2 and RIPK1 (Mus musculus)
TRADD [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:Q3U0V2
Reference Genes
BioGPS Gene:71609
ENSEMBL:ENSMUSG00000031887
ENSEMBL:ENSMUSG00000031887.14
KEGG Gene (Mus musculus):71609
Monarch:71609
NCBI Gene:71609
UCSC:Q3U0V2
Reference Transcript
RefSeq:NM_001033161.2
Other Identifiers
10581181
136534_at
1429117_at
1452622_a_at
160689_r_at
17512342
4419533
4452775
4538411
4654079
4675439
5103297
5192424
5387203
5442073
5580064
5594001
71609
A_51_P288505
GE40228
GO:0002947
GO:0005068
GO:0005164
GO:0005515
GO:0005634
GO:0005737
GO:0005856
GO:0005886
GO:0006915
GO:0006954
GO:0007165
GO:0007169
GO:0007249
GO:0008625
GO:0012501
GO:0019900
GO:0023052
GO:0030335
GO:0032728
GO:0032991
GO:0033209
GO:0035591
GO:0042802
GO:0042981
GO:0043123
GO:0043226
GO:0043235
GO:0044877
GO:0048856
GO:0048870
GO:0050729
GO:0051798
GO:0060090
GO:0070513
GO:0071356
GO:0097191
GO:1900119
ILMN_1233313
ILMN_2505100
mMC013666
Participates
as an input of
TRAF1 binds TRAF2 within TNFR1 signaling complex (Mus musculus)
TNF:TNFR1 binds TRADD, TRAF2 and RIPK1 (Mus musculus)
as a component of
TNFα:TNFR1:TRADD:K63,Met1polyUb, p-S25-RIPK1:BIRC2/3:p-S-CHUK:p-S-IKBKB:IKBKG [plasma membrane] (Mus musculus)
TNFalpha:TNFR1:TRADD:TRAF2:TRAF1:RIPK1 [plasma membrane] (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane] (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC [plasma membrane] (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
TRAF2:TRADD:RIPK1(325-671):FADD [cytosol] (Mus musculus)
TNF-α:TNFR1:TRADD:polyUb-RIPK1:TRAF2:MIB2 [plasma membrane] (Mus musculus)
TNF-alpha:TNFR1:TRADD:p-T189,K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane] (Mus musculus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Mus musculus)
TRAF2:TRADD:p-S320-RIPK1 [cytosol] (Mus musculus)
TRAF2:TRADD:p-S357-RIPK1 [cytosol] (Mus musculus)
TRAF2:TRADD:RIPK1 [cytosol] (Mus musculus)
Inferred From
TRADD [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001028333.1
Ensembl
ENSMUSG00000031887
,
ENSMUSP00000034359
,
ENSMUST00000034359
PRO
Q3U0V2
MGI
109200
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9QUK6
2
Tlr4 [endosome membrane]
(R-MMU-2201285)
Tlr4 [plasma membrane]
(R-MMU-166045)
0.499
3
UniProt:P01375 TNF
5
TNF(52-76) [extracellular region]
(R-HSA-8863375)
TNF(1-34) [plasma membrane]
(R-HSA-8863367)
TNF(1-76) [plasma membrane]
(R-HSA-8863120)
TNF(77-233) [extracellular region]
(R-HSA-976821)
TNF(1-233) [plasma membrane]
(R-HSA-66220)
0.499
2
UniProt:Q60855
14
K48polyUb-RIPK1 [cytosol]
(R-MMU-6783308)
PolyUb-RIPK1 [cytosol]
(R-MMU-6783197)
RIPK1 [cytosol]
(R-MMU-168651)
K63polyUb-RIPK1 [cytosol]
(R-MMU-937021)
phospho-p-S166-RIPK1 [cytosol]
(R-MMU-5218872)
phospho-p-S357-RIPK1 [cytosol]
(R-MMU-9819116)
phospho-p-S320-RIPK1 [cytosol]
(R-MMU-9815498)
phospho-K63,M1polyUb, p-T189-RIPK1 [cytosol]
(R-MMU-9817377)
polyUb-K377,K604,K634-RIPK1 [cytosol]
(R-MMU-9818391)
RIPK1(325-671) [cytosol]
(R-MMU-5212671)
RIPK1(1-324) [cytosol]
(R-MMU-5212664)
K63,M1polyUb-RIPK1 [cytosol]
(R-MMU-9793681)
phospho-K63,Met1polyUb-p-S25-RIPK1 [cytosol]
(R-MMU-9818793)
K48polyUb-K571,K604,K627-RIPK1 [cytosol]
(R-MMU-9796639)
0.499
2
UniProt:Q9QWL7
1
Krt17 [cytosol]
(R-MMU-201583)
0.488
2
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text