Reactome | Ub-ERCC6 [nucleoplasm]

Ub-ERCC6 [nucleoplasm]

Stable Identifier

R-MMU-6781853

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nucleoplasm

Synonyms

F8VPZ5

Locations in the PathwayBrowser

Expand all

DNA Repair (Mus musculus)

- Nucleotide Excision Repair (Mus musculus)
  - Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Mus musculus)
    - Formation of TC-NER Pre-Incision Complex (Mus musculus)
      - Assembly of the pre-incision complex in TC-NER (Mus musculus)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Mus musculus)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6 [nucleoplasm] (Mus musculus)
        
        Ub:ERCC6 [nucleoplasm] (Mus musculus)
        
        Ub-ERCC6 [nucleoplasm] (Mus musculus)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300 [nucleoplasm] (Mus musculus)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Mus musculus)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6 [nucleoplasm] (Mus musculus)
        
        Ub:ERCC6 [nucleoplasm] (Mus musculus)
        
        Ub-ERCC6 [nucleoplasm] (Mus musculus)
      - ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II (Mus musculus)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Mus musculus)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6 [nucleoplasm] (Mus musculus)
        
        Ub:ERCC6 [nucleoplasm] (Mus musculus)
        
        Ub-ERCC6 [nucleoplasm] (Mus musculus)
      - UVSSA:USP7 deubiquitinates ERCC6 (Mus musculus)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300 [nucleoplasm] (Mus musculus)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Mus musculus)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6 [nucleoplasm] (Mus musculus)
        
        Ub:ERCC6 [nucleoplasm] (Mus musculus)
        
        Ub-ERCC6 [nucleoplasm] (Mus musculus)

External Reference Information

External Reference

UniProt:F8VPZ5

Reference Genes

BioGPS Gene:319955

ENSEMBL:ENSMUSG00000054051

KEGG:mmu:319955

Monarch:319955

NCBI Gene:319955

UCSC:F8VPZ5

Reference Transcript

Other Identifiers

10413897

105115_at

1442604_at

17298585

319955

4323463

4371177

4439994

4476149

4598313

4601947

4610879

4768342

4774999

4820585

4828845

4845317

4882412

4884223

4902873

4929802

4972312

4997879

5023153

5023635

5033035

5078811

5108591

5112899

5150688

5152898

5161057

5240455

5248317

5254003

5296828

5326511

5338926

5348497

5349410

5404530

5432917

5437492

5469016

5494879

5506104

5506891

5520111

5558268

5562314

5605472

A_51_P254736

A_51_P442125

A_52_P1028440

A_55_P2839878

GE1499474

GO:0000012

GO:0000077

GO:0000303

GO:0003677

GO:0003682

GO:0003824

GO:0004386

GO:0005524

GO:0005634

GO:0005654

GO:0005730

GO:0006281

GO:0006283

GO:0006284

GO:0006290

GO:0006325

GO:0006338

GO:0006355

GO:0006362

GO:0006974

GO:0006979

GO:0007254

GO:0007399

GO:0008023

GO:0008094

GO:0008630

GO:0009411

GO:0009636

GO:0010165

GO:0010224

GO:0010332

GO:0016787

GO:0016887

GO:0022008

GO:0030154

GO:0030182

GO:0030296

GO:0031175

GO:0032784

GO:0032786

GO:0034243

GO:0035264

GO:0042262

GO:0043226

GO:0045494

GO:0045739

GO:0045943

GO:0045944

GO:0045945

GO:0048856

GO:0060261

GO:0090734

GO:0097680

GO:0098772

GO:0110016

GO:0140097

GO:0140657

GO:0140658

GO:1905168

GO:2001033

ILMN_1239263

ILMN_2688327

mMC020612

mMC022688

Participates

as a component of

Ub:ERCC6 [nucleoplasm] (Mus musculus)

Other forms of this molecule

ERCC6 [nucleoplasm]

Inferred From

Ub-ERCC6 [nucleoplasm] (Homo sapiens)

Modified Residues

Name

ubiquitinylated lysine at unknown position

PsiMod Name

ubiquitinylated lysine [MOD:01148]

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.

Cross References

ENSEMBL

ENSMUST00000066807, ENSMUSP00000066256, ENSMUSG00000054051

MGI

1100494

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