Reactome | PolyUb-DDX58 [cytosol]

PolyUb-DDX58 [cytosol]

Stable Identifier

R-MMU-6782770

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

Q6Q899

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q6Q899 Rigi

Gene Names

Rigi, Ddx58

Chain

chain:1-926

Reference Genes

BioGPS Gene:230073 Rigi

KEGG:mmu:230073 Rigi

Monarch:230073 Rigi

NCBI Gene:230073 Rigi

UCSC:Q6Q899 Rigi

Reference Transcript

RefSeq:NM_172689.3 Rigi

Other Identifiers

10512067

110124_at

1436562_at

1446457_at

1456890_at

17423987

230073

4339227

4378342

4388817

4442601

4525571

4549889

4572114

4589369

4599329

4605603

4616105

4744678

4826751

4883951

4894834

5033421

5044724

5045640

5047486

5059209

5077455

5077602

5098647

5116175

5179483

5183152

5221244

5259364

5282690

5493727

5601459

5607409

A_51_P393748

A_52_P385536

A_52_P479001

A_52_P523946

A_55_P1965000

A_55_P2609358

GE137979

GE1459986

GO:0002230

GO:0002376

GO:0002735

GO:0002753

GO:0003676

GO:0003677

GO:0003690

GO:0003723

GO:0003724

GO:0003725

GO:0003727

GO:0003824

GO:0004386

GO:0005515

GO:0005524

GO:0005525

GO:0005737

GO:0005829

GO:0005856

GO:0005886

GO:0005923

GO:0006355

GO:0008270

GO:0009597

GO:0009615

GO:0010467

GO:0010628

GO:0015629

GO:0016787

GO:0016887

GO:0030334

GO:0031625

GO:0032587

GO:0032725

GO:0032727

GO:0032728

GO:0032755

GO:0032757

GO:0032760

GO:0038187

GO:0039529

GO:0042802

GO:0042995

GO:0043226

GO:0043330

GO:0045087

GO:0045944

GO:0046872

GO:0051607

GO:0060089

GO:0060760

GO:0071360

GO:0098542

GO:0140098

GO:0140374

GO:0140657

GO:1990904

ILMN_1234367

ILMN_1239996

ILMN_1240856

ILMN_1251358

ILMN_2582659

ILMN_2717127

mMC002496

mMR030864

Participates

as a member of

as a component of

USP25:PolyUb-DDX58 [cytosol] (Mus musculus)

Other forms of this molecule

Rig-I [cytosol]

K63polyUb-DDX58 [cytosol]

DDX58 [cytosol]

Inferred From

PolyUb-DDX58 [cytosol] (Homo sapiens)

Modified Residues

Name

ubiquitinylated lysine (PolyUb [cytosol]) at unknown position

Modification

PolyUb [cytosol]

PsiMod Name

ubiquitinylated lysine [MOD:01148]

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.

Cross References

RefSeq

NP_766277.3

ENSEMBL

ENSMUSP00000042433, ENSMUST00000037907

IntEnz

3.6.4.13

PRO

Q6Q899

GlyGen

Q6Q899

MGI

2442858

PDB

6BZH, 3TBK

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q80ZE3	3	SIGLEC11 [plasma membrane] (R-MMU-197709) SIGLEC10 [plasma membrane] (R-MMU-197707) SIGLEC16 [plasma membrane] (R-MMU-2326826)	0.537	7
UniProt:P22682 Cbl	8	Cbl [cytosol] (R-MMU-9680636) p-Y-Cbl [cytosol] (R-MMU-9680645) phospho-p-Y-CBL [cytosol] (R-MMU-8875457) phospho-p-Y371-CBL [plasma membrane] (R-MMU-182923) phospho-PolyUb,p-Y700,Y731,Y774-CBL [cytosol] (R-MMU-8848826) phospho-p-Y700,Y731,Y774-CBL [cytosol] (R-MMU-912656) phospho-p-Y371-CBL [cytosol] (R-MMU-182940) CBL [cytosol] (R-MMU-112199)	0.537	3
UniProt:P35235 Ptpn11	5	p-Y546,Y584-Shp2 [cytosol] (R-MMU-443116) Ptpn11 [cytosol] (R-MMU-210002) PTPN11 [nucleoplasm] (R-MMU-8937745) PTPN11 [cytosol] (R-MMU-162563) phospho-p-Y542,Y580-PTPN11 [cytosol] (R-MMU-162573)	0.462	4