Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
Ripk1 [cytosol]
Stable Identifier
R-MMU-6783308
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
K48polyUb-RIPK1, Q60855
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Mus musculus)
Post-translational protein modification (Mus musculus)
Deubiquitination (Mus musculus)
Ovarian tumor domain proteases (Mus musculus)
TNFAIP3 (A20) ubiquitinates RIPK1 (Mus musculus)
TNFAIP3:K48polyUb-RIPK1 [cytosol] (Mus musculus)
Ripk1 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:Q60855
Gene Names
Ripk1
Reference Genes
BioGPS Gene:19766 Ripk1
ENSEMBL:ENSMUSG00000021408
KEGG Gene (Mus musculus):19766 Ripk1
Monarch:19766 Ripk1
NCBI Gene:19766 Ripk1
UCSC:Q60855 Ripk1
Reference Transcript
RefSeq:NM_009068.3 Ripk1
RefSeq:XM_006516609.3 Ripk1
RefSeq:XM_006516607.3 Ripk1
Other Identifiers
10404506
130183_at
1419508_at
1439273_at
1449485_at
17286472
19766
4387682
4499854
4576677
4587400
4619144
4679401
4705696
4738836
4769386
4792006
4886540
4937728
4942812
4968495
4977703
5073064
5165706
5165855
5170973
5475993
5598996
5609742
97091_at
AA186144_at
A_51_P430952
A_52_P174775
A_52_P452740
GE33576
GO:0000166
GO:0000278
GO:0001934
GO:0002376
GO:0003674
GO:0004672
GO:0004674
GO:0004706
GO:0005123
GO:0005515
GO:0005524
GO:0005575
GO:0005622
GO:0005737
GO:0005739
GO:0005829
GO:0005886
GO:0006464
GO:0006468
GO:0006810
GO:0006915
GO:0006950
GO:0006954
GO:0007049
GO:0007165
GO:0007256
GO:0007257
GO:0008150
GO:0008219
GO:0008283
GO:0009056
GO:0009058
GO:0010940
GO:0010942
GO:0012501
GO:0016020
GO:0016032
GO:0016301
GO:0016310
GO:0016740
GO:0019899
GO:0022607
GO:0030154
GO:0031264
GO:0031625
GO:0032757
GO:0032760
GO:0032991
GO:0034612
GO:0034641
GO:0036289
GO:0040007
GO:0042327
GO:0042802
GO:0042803
GO:0043065
GO:0043066
GO:0043068
GO:0043123
GO:0043124
GO:0043167
GO:0043226
GO:0043235
GO:0043410
GO:0044257
GO:0044403
GO:0044877
GO:0045121
GO:0045651
GO:0045944
GO:0046330
GO:0046777
GO:0048856
GO:0050729
GO:0051092
GO:0055085
GO:0060044
GO:0060545
GO:0060546
GO:0065003
GO:0070105
GO:0070231
GO:0070266
GO:0070301
GO:0070513
GO:0070926
GO:0071356
GO:0071363
GO:0097191
GO:0097300
GO:0097342
GO:0097343
GO:0097527
GO:1901026
GO:1903265
GO:1903800
GO:1905206
GO:1990000
GO:2000134
GO:2000377
GO:2001237
GO:2001238
GO:2001240
ILMN_2753492
U25995_s_at
mMR026803
Participant Of
hasComponent
TNFAIP3:K48polyUb-RIPK1 [cytosol]
Other forms of this molecule
Ripk1 [cytosol]
Ripk1 [cytosol]
Ripk1 [cytosol]
phospho-Ripk1 [cytosol]
Ripk1 [cytosol]
Ripk1 [cytosol]
Inferred From
K48polyUb-RIPK1 [cytosol] (Homo sapiens)
Modified Residues
Name
ubiquitinylated lysine (K48polyUb [cytosol]) at unknown position
Modification
K48polyUb [cytosol]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
XP_006516672.1
,
XP_006516670.1
,
NP_033094.3
Ensembl
ENSMUSP00000021844
,
ENSMUST00000167374
,
ENSMUST00000021844
,
ENSMUSG00000021408
,
ENSMUSP00000129831
PRO
Q60855
MGI
108212
Interactors (8)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q61160
1
Fadd [cytosol]
(R-MMU-54639)
0.886
8
UniProt:P25118
1
Tnfrsf1a [plasma membrane]
(R-MMU-66344)
0.669
3
UniProt:P62991 UBIQ
0.667
5
UniProt:Q9QZL0
7
Ripk3 [cytosol]
(R-MMU-9687819)
phospho-Ripk3 [cytosol]
(R-MMU-9686933)
Ripk3 [cytosol]
(R-MMU-9686937)
Ripk3 [cytosol]
(R-MMU-9686917)
Ripk3 [cytosol]
(R-MMU-9688825)
phospho-Ripk3 [cytosol]
(R-MMU-5218873)
Ripk3 [cytosol]
(R-MMU-450328)
0.589
4
UniProt:Q3U0V2
1
Tradd [cytosol]
(R-MMU-66376)
0.499
2
UniProt:P01375 TNF
5
TNF(1-34) [plasma membrane]
(R-HSA-8863367)
TNF(52-76) [extracellular region]
(R-HSA-8863375)
TNF(1-76) [plasma membrane]
(R-HSA-8863120)
TNF(77-233) [extracellular region]
(R-HSA-976821)
TNF(1-233) [plasma membrane]
(R-HSA-66220)
0.499
3
UniProt:P33896 Ifnar1
3
Ifnar1 [plasma membrane]
(R-MMU-877334)
Ifnar1 [plasma membrane]
(R-MMU-912671)
phospho-Ifnar1 [plasma membrane]
(R-MMU-909675)
0.463
2
UniProt:P47741
1
Tnfrsf4 [plasma membrane]
(R-MMU-5692210)
0.462
7
© 2021
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text