Reactome | Nabp2 [nucleoplasm]

Nabp2 [nucleoplasm]

Stable Identifier

R-MMU-6814916

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nucleoplasm

Synonyms

NABP2, Q8R2Y9

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Mus musculus)

- RNA Polymerase II Transcription (Mus musculus)
  - RNA polymerase II transcribes snRNA genes (Mus musculus)
    - CBCAP complex binds 7-methylguanosine cap of snRNA (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Mus musculus)
        
        Integrator [nucleoplasm] (Mus musculus)
        
        NABP1,2 [nucleoplasm] (Mus musculus)
        
        Nabp2 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Mus musculus)
        
        Integrator [nucleoplasm] (Mus musculus)
        
        NABP1,2 [nucleoplasm] (Mus musculus)
        
        Nabp2 [nucleoplasm] (Mus musculus)
    - Integrator complex processes the 3' end of snRNA (Mus musculus)
      - Integrator [nucleoplasm] (Mus musculus)
        
        NABP1,2 [nucleoplasm] (Mus musculus)
        
        Nabp2 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Mus musculus)
        
        Integrator [nucleoplasm] (Mus musculus)
        
        NABP1,2 [nucleoplasm] (Mus musculus)
        
        Nabp2 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Mus musculus)
        
        Integrator [nucleoplasm] (Mus musculus)
        
        NABP1,2 [nucleoplasm] (Mus musculus)
        
        Nabp2 [nucleoplasm] (Mus musculus)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Mus musculus)
        
        Integrator [nucleoplasm] (Mus musculus)
        
        NABP1,2 [nucleoplasm] (Mus musculus)
        
        Nabp2 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Mus musculus)
        
        Integrator [nucleoplasm] (Mus musculus)
        
        NABP1,2 [nucleoplasm] (Mus musculus)
        
        Nabp2 [nucleoplasm] (Mus musculus)
    - Pre-snRNA transcript initiation, Integrator binding, LEC binding (Mus musculus)
      - Integrator [nucleoplasm] (Mus musculus)
        
        NABP1,2 [nucleoplasm] (Mus musculus)
        
        Nabp2 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Mus musculus)
        
        Integrator [nucleoplasm] (Mus musculus)
        
        NABP1,2 [nucleoplasm] (Mus musculus)
        
        Nabp2 [nucleoplasm] (Mus musculus)

External Reference Information

External Reference

UniProt:Q8R2Y9

Gene Names

Nabp2

Reference Genes

BioGPS Gene:69917 Nabp2

ENSEMBL:ENSMUSG00000025374

ENSEMBL:ENSMUSG00000025374.14 Nabp2

KEGG Gene (Mus musculus):69917 Nabp2

Monarch:69917 Nabp2

NCBI Gene:69917 Nabp2

UCSC:Q8R2Y9 Nabp2

Reference Transcript

Other Identifiers

10373388

114020_at

1451291_at

17246131

4371820

4516070

4829391

4883179

4899980

5020779

5051051

5097963

5145629

5298653

5428594

5495748

69917

A_51_P294883

A_55_P2004588

A_55_P2486214

GO:0000278

GO:0000724

GO:0000781

GO:0003676

GO:0003677

GO:0003697

GO:0005634

GO:0005654

GO:0005694

GO:0005829

GO:0006281

GO:0006310

GO:0006974

GO:0010212

GO:0023052

GO:0032200

GO:0035861

GO:0043226

GO:0044818

GO:0070182

GO:0070200

GO:0070876

GO:0098505

GO:1904355

ILMN_2593852

ILMN_2837156

mMC010697

Participates

as a member of

NABP1,2 [nucleoplasm] (Mus musculus)

Inferred From

NABP2 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_006514131.1, NP_081533.1, XP_006514129.1, XP_006514130.1

Ensembl

ENSMUSP00000128634, ENSMUST00000164199, ENSMUST00000026439, ENSMUSG00000025374, ENSMUSP00000026439

PRO

Q8R2Y9

MGI

1917167

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