Reactome | Snapc4 [nucleoplasm]

Snapc4 [nucleoplasm]

Stable Identifier

R-MMU-83729

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nucleoplasm

Synonyms

SNAPC4, Q8BP86

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Mus musculus)

- RNA Polymerase II Transcription (Mus musculus)
  - RNA polymerase II transcribes snRNA genes (Mus musculus)
    - CBCAP complex binds 7-methylguanosine cap of snRNA (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc4 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc4 [nucleoplasm] (Mus musculus)
    - CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Mus musculus)
      - RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc4 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc4 [nucleoplasm] (Mus musculus)
    - General transcription factors bind SNAPc:POU2F1:ZNF143:snRNA gene (Mus musculus)
      - Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc4 [nucleoplasm] (Mus musculus)
      - SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc4 [nucleoplasm] (Mus musculus)
    - Integrator complex processes the 3' end of snRNA (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc4 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc4 [nucleoplasm] (Mus musculus)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc4 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc4 [nucleoplasm] (Mus musculus)
    - Pre-snRNA transcript initiation, Integrator binding, LEC binding (Mus musculus)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc4 [nucleoplasm] (Mus musculus)
      - RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc4 [nucleoplasm] (Mus musculus)
    - RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Mus musculus)
      - Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc4 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc4 [nucleoplasm] (Mus musculus)
    - RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain (Mus musculus)
      - RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc4 [nucleoplasm] (Mus musculus)
      - RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc4 [nucleoplasm] (Mus musculus)
- RNA Polymerase III Transcription (Mus musculus)
  - RNA Polymerase III Transcription Initiation (Mus musculus)
    - RNA Polymerase III Transcription Initiation From Type 3 Promoter (Mus musculus)
      - Binding of TFIIIB to SNAPc:Oct-1:Staf:Type 3 Promoter Complex (Mus musculus)
        
        SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc4 [nucleoplasm] (Mus musculus)
        
        TFIIIB:SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Mus musculus)
        
        SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc4 [nucleoplasm] (Mus musculus)
      - Recruitment of RNA Polymerase III to TFIIIB:SNAPc:Type 3 Promoter Complex (Mus musculus)
        
        RNA Polymerase III:TFIIIB:SNAPc:Type 3 Promoter Complex [nucleoplasm] (Mus musculus)
        
        TFIIIB:SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Mus musculus)
        
        SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc4 [nucleoplasm] (Mus musculus)
        
        TFIIIB:SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Mus musculus)
        
        SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc4 [nucleoplasm] (Mus musculus)

External Reference Information

External Reference

UniProt:Q8BP86

Gene Names

Snapc4

Reference Genes

BioGPS Gene:227644 Snapc4

ENSEMBL:ENSMUSG00000036281

ENSEMBL:ENSMUSG00000036281.14 Snapc4

KEGG Gene (Mus musculus):227644 Snapc4

Monarch:227644 Snapc4

NCBI Gene:227644 Snapc4

UCSC:Q8BP86 Snapc4

Reference Transcript

Other Identifiers

10480971

110635_at

1441795_at

1455552_at

17382937

227644

4373212

4435691

4445181

4466654

4506376

4525233

4617409

4618968

4632459

4638753

4706641

4735612

4764855

4816394

4824539

4922171

5038461

5059088

5076046

5090864

5105352

5284497

5295824

5300352

5306744

5313814

5337332

5345349

5364834

5581869

5608259

5608463

A_51_P349036

A_55_P2093543

GE1512484

GO:0000978

GO:0000995

GO:0001006

GO:0003677

GO:0005634

GO:0006351

GO:0016073

GO:0016251

GO:0019185

GO:0042795

GO:0042796

GO:0043226

GO:0140223

ILMN_2675433

mMC019305

Participates

as a component of

SNAPc [nucleoplasm] (Mus musculus)

Inferred From

SNAPC4 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_001277348.1, NP_758842.1

Ensembl

ENSMUSP00000041767, ENSMUST00000035427, ENSMUSG00000036281

PRO

Q8BP86

MGI

2443935

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