Expression of Dbp

Stable Identifier
R-MMU-879748
Type
Reaction [omitted]
Species
Mus musculus
Compartment
nucleoplasm
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Expression of Dbp
The Dbp gene is transcribed to yield mRNA and the mRNA is translated to yield protein. Bmal1:Clock (Arntl:Clock) heterodimers binds E-boxes in the promoter of Dbp and activate transcription of Dbp.
Literature References
PubMed ID Title Journal Year
10733528 CLOCK, an essential pacemaker component, controls expression of the circadian transcription factor DBP

Schibler, U, Reppert, SM, Shearman, LP, Ripperger, JA

Genes Dev 2000
16474407 Rhythmic CLOCK-BMAL1 binding to multiple E-box motifs drives circadian Dbp transcription and chromatin transitions

Schibler, U, Ripperger, JA

Nat Genet 2006
Participants
Input
Output
This event is regulated
Positively by
Regulator
p-Bmal1:p-Clock,Npas2:Dbp gene [nucleoplasm] (Mus musculus)
Orthologous Events
Expression of DBP (Homo sapiens)
Authored
May, B  (2010-06-18)
Reviewed
Delaunay, F  (2010-06-23)
Kay, SA  (2010-06-23)
Hirota, T  (2010-06-23)
Albrecht, U  (2010-06-23)
Created
May, B  (2010-06-23)
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