Reactome | phospho-H3c8 [nucleoplasm]

phospho-H3c8 [nucleoplasm]

Stable Identifier

R-MMU-8871295

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nucleoplasm

Synonyms

AcK14,18-p-S10-HIST1H3A, P68433

Locations in the PathwayBrowser

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Immune System (Mus musculus)

- Cytokine Signaling in Immune system (Mus musculus)
  - Signaling by Interleukins (Mus musculus)
    - Interleukin-7 signaling (Mus musculus)
      - BRWD1 binds AcK(9,14,18,79)-p(S10,T11)-histone H3 (Mus musculus)
        
        AcK(9,14,18,79)-p(S10,T11)-histone H3 [nucleoplasm] (Mus musculus)
        
        AcK14,18-p-S10-histone H3 [nucleoplasm] (Mus musculus)
        
        phospho-H3c8 [nucleoplasm] (Mus musculus)
        
        BRWD1:AcK(9,14,18,79)-p(S10,T11)-histone H3 [nucleoplasm] (Mus musculus)
        
        AcK(9,14,18,79)-p(S10,T11)-histone H3 [nucleoplasm] (Mus musculus)
        
        AcK14,18-p-S10-histone H3 [nucleoplasm] (Mus musculus)
        
        phospho-H3c8 [nucleoplasm] (Mus musculus)

External Reference Information

External Reference

UniProt:P68433 H3c1

Gene Names

H3c1, H3a, Hist1h3a, H3c8, H3.1-221, H3g, Hist1h3g, H3c10, H3.1-291, H3h, Hist1h3h, H3c11, H3.1-I, H3i, Hist1h3i

Chain

initiator methionine:1, chain:2-136

Reference Genes

BioGPS Gene:319152 H3c1

BioGPS Gene:319153 H3c1

BioGPS Gene:360198 H3c1

BioGPS Gene:97908 H3c1

ENSEMBL:ENSMUSG00000069265 H3c1

ENSEMBL:ENSMUSG00000099517 H3c1

ENSEMBL:ENSMUSG00000101355 H3c1

ENSEMBL:ENSMUSG00000101972 H3c1

KEGG Gene (Mus musculus):319152 H3c1

KEGG Gene (Mus musculus):319153 H3c1

KEGG Gene (Mus musculus):360198 H3c1

KEGG Gene (Mus musculus):97908 H3c1

Monarch:319152 H3c1

Monarch:319153 H3c1

Monarch:360198 H3c1

Monarch:97908 H3c1

NCBI Gene:319152 H3c1

NCBI Gene:319153 H3c1

NCBI Gene:360198 H3c1

NCBI Gene:97908 H3c1

UCSC:P68433 H3c1

Reference Transcript

Other Identifiers

10403941

10404028

10404049

10404065

10408083

10408202

10408239

10408246

10494405

1443475_at

1460314_s_at

17285680

17285821

17291008

17291233

319152

319153

360198

4338913

4461543

4512508

4705230

4804380

4859434

5032897

5080056

5150983

5167684

5313600

5455398

5463715

5495524

93023_f_at

96416_f_at

97908

A_51_P518621

A_55_P2068260

A_55_P2121521

GE130606

GO:0000228

GO:0000786

GO:0003674

GO:0003677

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005694

GO:0006334

GO:0006335

GO:0008150

GO:0022607

GO:0032991

GO:0043226

GO:0046982

GO:0051276

GO:0060968

GO:0065003

ILMN_2592253

ILMN_2697777

ILMN_2698519

ILMN_2777961

ILMN_2860616

ILMN_2951691

ILMN_3002290

mMC014410

mMC019528

mMC024888

mMC025496

mMC026072

Participates

as a member of

AcK14,18-p-S10-histone H3 [nucleoplasm] (Mus musculus)

Other forms of this molecule

H3c8 [nucleoplasm]

AcK15-histone H3.1 [nucleoplasm]

H3c8 [nucleoplasm]

AcK9,14-p-S10-histone H3.1 [nucleoplasm]

phospho-H3c8 [nucleoplasm]

H3c8 [nucleoplasm]

H3c8 [cytosol]

H3c8 [nucleoplasm]

AcK10-Hist1h3a [nucleoplasm]

H3c8 [nucleoplasm]

phospho-H3c8 [nucleoplasm]

H3c8 [nucleoplasm]

phospho-H3c8 [nucleoplasm]

Me2K10-Hist1h3a [nucleoplasm]

Me3K5-Hist1h3a [nucleoplasm]

Histone H3.1 [nucleoplasm]

Me3K28-Hist1h3a [nucleoplasm]

Me2K5-Hist1h3a [nucleoplasm]

Inferred From

AcK14,18-p-S10-HIST1H3A [nucleoplasm] (Homo sapiens)

Modified Residues

Name

N6-acetyl-L-lysine at 15

Coordinate

PsiMod Name

N6-acetyl-L-lysine [MOD:00064]

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to N6-acetyl-L-lysine.

Name

N6-acetyl-L-lysine at 19 (in Homo sapiens)

Coordinate

PsiMod Name

N6-acetyl-L-lysine [MOD:00064]

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to N6-acetyl-L-lysine.

Name

O-phospho-L-serine at 11

Coordinate

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Cross References

RefSeq

NP_835514.1, NP_659539.1, NP_038578.2, NP_835513.1

Ensembl

ENSMUSP00000079670, ENSMUSG00000069265, ENSMUSG00000101972, ENSMUSP00000139663, ENSMUSG00000099517, ENSMUSP00000089293, ENSMUST00000091701, ENSMUST00000188775, ENSMUSP00000140394, ENSMUST00000189457, ENSMUST00000080859, ENSMUSG00000101355

PRO

P68433

MGI

2668828, 2145541, 2448349, 2448350

PDB

5IX2, 5IX1, 2W5Z, 4EZH, 2XL3, 2V83, 2WP1, 5B1M, 5B1L, 1U35, 1GUW

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P83917 CBX1			0.676	6
UniProt:Q8WTS6 SETD7	1	SETD7 [nucleoplasm] (R-HSA-1183221)	0.558	2