Il23r binds Jak2

Stable Identifier
R-MMU-8950723
Type
Reaction [binding]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Il23r binds Jak2

Interleukin-23 heterodimeric receptor ,formed by Interleukin-23 receptor (IL23R) and Interleukin-12 receptor beta 1 subunit (IL12RB1), can bind Tyrosine-protein kinase JAK2(Jak2). This association is mandatory for Interleukin-23 signaling (Floss et al. 2016).

Literature References
PubMed ID Title Journal Year
27193299 Defining the functional binding sites of interleukin 12 receptor β1 and interleukin 23 receptor to Janus kinases

Floss, DM, Klöcker, T, Schröder, J, Lamertz, L, Mrotzek, S, Strobl, B, Hermanns, H, Scheller, J

Mol. Biol. Cell 2016
Participants
Orthologous Events
Authored
Reviewed
Created