Socs3 gene expression is inhibited by Runx1

Stable Identifier
R-MMU-8955856
Type
Reaction [omitted]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Socs3 gene expression is inhibited by Runx1

Based on studies in mouse keratinocytes, Runx1, presumably in complex with Cbfb, inhibits transcription of the Socs3 gene by binding to Runx response elements within the Socs3 gene locus (Scheitz et al. 2012).

Literature References
PubMed ID Title Journal Year
23034403 Defining a tissue stem cell-driven Runx1/Stat3 signalling axis in epithelial cancer

Scheitz, CJ, Lee, TS, McDermitt, DJ, Tumbar, T

EMBO J. 2012
Participants
This event is regulated
Orthologous Events
Authored
Reviewed
Created