Grin2a gene expression is stimulated by Mecp2

Stable Identifier
R-MMU-9006510
Type
Reaction [omitted]
Species
Mus musculus
Compartment
nucleoplasm, plasma membrane
ReviewStatus
5/5
General
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PNG
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 | PPTX  | SBGN
Grin2a gene expression is stimulated by Mecp2
Mouse Mecp2 stimulates transcription of the mouse Grin2a gene, encoding NMDA receptor 2A. Grin2a expression is decreased in Mecp2 knockout mice (Durand et al. 2012).
Literature References
PubMed ID Title Journal Year
23259945 NMDA receptor regulation prevents regression of visual cortical function in the absence of Mecp2

Patrizi, A, Quast, KB, Hensch, TK, Pavlyuk, R, Fagiolini, M, Carninci, P, Saxena, A, Durand, S, Hachigian, L

Neuron 2012
Participants
Input
Output
This event is regulated
Positively by
Regulator
Mecp2:Grin2a gene [nucleoplasm] (Mus musculus)
Active Unit
Mecp2 [nucleoplasm]
Orthologous Events
GRIN2A gene expression is stimulated by MECP2 (Homo sapiens)
Authored
Orlic-Milacic, M  (2017-10-02)
Reviewed
Krishnaraj, R  (2018-08-07)
Christodoulou, J  (2018-08-07)
Created
Orlic-Milacic, M  (2017-05-16)
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