Robo3 binds Nell2

Stable Identifier
R-MMU-9010205
Type
Reaction [binding]
Species
Mus musculus
Compartment
plasma membrane
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Robo3 binds Nell2
In mice, Robo3 isoforms Robo3.1 and Robo3.2 bind to a secreted ligand Nell2 (neural epidermal growth factor-like-like 2). This interaction involves the EGF-like domains of Nell2 and the FN3 (FNIII) domain of Robo3 (Jaworski et al. 2015).
Literature References
PubMed ID Title Journal Year
26586761 Operational redundancy in axon guidance through the multifunctional receptor Robo3 and its ligand NELL2

Jaworski, A, Tong, RK, Gildea, HK, Tom, I, Gonzalez, LC, Koch, AW, Tessier-Lavigne, M

Science 2015
Participants
Input
Output
Orthologous Events
ROBO3 binds NELL2 (Homo sapiens)
Authored
Orlic-Milacic, M  (2017-06-26)
Reviewed
Jaworski, A  (2017-07-31)
Created
Orlic-Milacic, M  (2017-06-26)
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