Fabp7 gene expression is positively regulated by Notch1 and Notch3

Stable Identifier
R-MMU-9016782
Type
Reaction [omitted]
Species
Mus musculus
Compartment
nucleoplasm, cytosol
ReviewStatus
5/5
General
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PNG
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 | PPTX  | SBGN
Fabp7 gene expression is positively regulated by Notch1 and Notch3
Expression of Fabp7 (Blbp) in mouse radial glia is positively regulated by Notch1 and Notch3 during neuronal migration (Anthony et al. 2005, Keilani and Sugaya 2008). The promoter of the mouse Fabp7 gene contains an RbpJ binding site needed for Fabp7 expression (Anthony et al. 2005).
Literature References
PubMed ID Title Journal Year
18593473 Reelin induces a radial glial phenotype in human neural progenitor cells by activation of Notch-1

Sugaya, K, Keilani, S

BMC Dev. Biol. 2008
15879553 Brain lipid-binding protein is a direct target of Notch signaling in radial glial cells

Gridley, T, Heintz, N, Fishell, G, Mason, HA, Anthony, TE

Genes Dev. 2005
Participants
Input
Output
This event is regulated
Positively by
Regulator
Notch1/Notch3 coactivator complex [nucleoplasm] (Mus musculus)
Orthologous Events
FABP7 gene expression is positively regulated by NOTCH1 and NOTCH3 (Homo sapiens)
Authored
Orlic-Milacic, M  (2017-09-20)
Reviewed
Haw, R  (2017-10-30)
Created
Orlic-Milacic, M  (2017-08-15)
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