Epo:p-8Y-Epor:p-12Y-Jak2:Lyn:Irs2:p-Crkl:Rapgef1 binds Shc1

Stable Identifier
R-MMU-9027266
Type
Reaction [binding]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Epo:p-8Y-Epor:p-12Y-Jak2:Lyn:Irs2:p-Crkl:Rapgef1 binds Shc1

After stimulation by Epo, Crkl associates with Epor, is phosphorylated, and binds Shc1 (Miura et al. 1994, Chin et al. 1997).

Literature References
PubMed ID Title Journal Year
9344843 Erythropoietin and IL-3 induce tyrosine phosphorylation of CrkL and its association with Shc, SHP-2, and Cbl in hematopoietic cells

Chin, H, Saito, T, Arai, A, Yamamoto, K, Kamiyama, R, Miyasaka, N, Miura, O

Biochem. Biophys. Res. Commun. 1997
7961995 Activation of the mitogen-activated protein kinase pathway by the erythropoietin receptor

Miura, Y, Miura, O, Ihle, JN, Aoki, N

J. Biol. Chem. 1994
Participants
Orthologous Events
Authored
Reviewed
Created
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