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Dock3 binds Fyn associated with Ntrk2
Stable Identifier
R-MMU-9032771
Type
Reaction [omitted]
Species
Mus musculus
Compartment
plasma membrane
,
cytosol
ReviewStatus
5/5
General
SBML
|
BioPAX
Level 2
Level 3
|
PDF
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|
PNG
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SBGN
Activation of mouse Ntrk2 (TrkB) with recombinant mouse Bdnf results in recruitment of recombinant mouse Dock3 to activated recombinant mouse Fyn (Namekata et al. 2010).
Literature References
PubMed ID
Title
Journal
Year
20368433
Dock3 induces axonal outgrowth by stimulating membrane recruitment of the WAVE complex
Harada, T
,
Namekata, K
,
Guo, X
,
Harada, C
,
Parada, LF
,
Kimura, H
,
Taya, C
Proc. Natl. Acad. Sci. U.S.A.
2010
Participants
Input
Bdnf:p-5Y-Ntrk2 homodimer:MyrG,p-Y420-Fyn [plasma membrane]
(Mus musculus)
Dock3 [cytosol]
(Mus musculus)
Output
Bdnf:p-5Y-Ntrk2 homodimer:MyrG,p-Y420-FYN-1:DOCK3 [plasma membrane]
(Mus musculus)
Orthologous Events
DOCK3 binds FYN associated with NTRK2 (Homo sapiens)
Authored
Orlic-Milacic, M (2018-01-05)
Reviewed
Castrén, E (2018-02-13)
Antila, H (2018-02-13)
Created
Orlic-Milacic, M (2017-12-18)
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