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phospho-Ifnar1 [plasma membrane]
Stable Identifier
R-MMU-909675
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
plasma membrane
Synonyms
p-Y466,Y481-IFNAR1, P33896
Locations in the PathwayBrowser
Expand all
Immune System (Mus musculus)
Cytokine Signaling in Immune system (Mus musculus)
Interferon Signaling (Mus musculus)
Interferon alpha/beta signaling (Mus musculus)
Activation of JAK kinases (Mus musculus)
p-TYK2:p-IFNAR1:SOCS-1/SOCS-3:IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Mus musculus)
p-IFNAR1:p-TYK2:SOCS-1/SOCS-3 [plasma membrane] (Mus musculus)
phospho-Ifnar1 [plasma membrane] (Mus musculus)
Formation of p-STAT1 homodimer (Mus musculus)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2 [plasma membrane] (Mus musculus)
p-STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Mus musculus)
phospho-Ifnar1 [plasma membrane] (Mus musculus)
Phosphorylation of INFAR1 by TYK2 (Mus musculus)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Mus musculus)
p-IFNAR1:p-TYK2 [plasma membrane] (Mus musculus)
phospho-Ifnar1 [plasma membrane] (Mus musculus)
Phosphorylation of STAT2 (Mus musculus)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:STAT2 [plasma membrane] (Mus musculus)
STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Mus musculus)
phospho-Ifnar1 [plasma membrane] (Mus musculus)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2 [plasma membrane] (Mus musculus)
p-STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Mus musculus)
phospho-Ifnar1 [plasma membrane] (Mus musculus)
Recruitment of STAT2 to p-IFNAR1 (Mus musculus)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Mus musculus)
p-IFNAR1:p-TYK2 [plasma membrane] (Mus musculus)
phospho-Ifnar1 [plasma membrane] (Mus musculus)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:STAT2 [plasma membrane] (Mus musculus)
STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Mus musculus)
phospho-Ifnar1 [plasma membrane] (Mus musculus)
Regulation of IFNA/IFNB signaling (Mus musculus)
Dephosphorylation of STAT1 by SHP2 (Mus musculus)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:STAT1 [plasma membrane] (Mus musculus)
p-STAT2:STAT1:p-IFNAR1:p-TYK2 [plasma membrane] (Mus musculus)
phospho-Ifnar1 [plasma membrane] (Mus musculus)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane] (Mus musculus)
p-STAT2:p-STAT1:p-IFNAR1:p-TYK2 [plasma membrane] (Mus musculus)
phospho-Ifnar1 [plasma membrane] (Mus musculus)
Release of p-STAT2:p-STAT1 dimer (Mus musculus)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Mus musculus)
p-IFNAR1:p-TYK2 [plasma membrane] (Mus musculus)
phospho-Ifnar1 [plasma membrane] (Mus musculus)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane] (Mus musculus)
p-STAT2:p-STAT1:p-IFNAR1:p-TYK2 [plasma membrane] (Mus musculus)
phospho-Ifnar1 [plasma membrane] (Mus musculus)
External Reference Information
External Reference
UniProt:P33896 Ifnar1
Gene Names
Ifnar1, Ifar, Ifnar
Chain
signal peptide:1-26, chain:27-590
Reference Genes
BioGPS Gene:15975 Ifnar1
ENSEMBL:ENSMUSG00000022967.14 Ifnar1
KEGG Gene (Mus musculus):15975 Ifnar1
Monarch:15975 Ifnar1
NCBI Gene:15975 Ifnar1
UCSC:P33896 Ifnar1
Reference Transcript
RefSeq:NM_010508.2 Ifnar1
Other Identifiers
100483_at
10436849
1449026_at
15975
17327069
4383843
4457939
4635829
4641021
4676471
4722217
4745403
4754188
4826694
4875597
5019050
5041934
5123215
5151377
5193669
5242128
5275975
5364415
5447591
5505493
5519241
5578715
A_51_P168545
A_55_P2438722
GE35588
GO:0002376
GO:0004904
GO:0004905
GO:0005515
GO:0005764
GO:0005768
GO:0005770
GO:0005773
GO:0005886
GO:0006091
GO:0006351
GO:0006355
GO:0007259
GO:0008269
GO:0010467
GO:0016020
GO:0019221
GO:0019955
GO:0019962
GO:0023052
GO:0031410
GO:0032496
GO:0032728
GO:0032729
GO:0032731
GO:0035457
GO:0035458
GO:0036211
GO:0042110
GO:0043226
GO:0045893
GO:0046425
GO:0050730
GO:0051607
GO:0060089
GO:0060090
GO:0060337
GO:0098542
GO:1901857
ILMN_1222758
m89641_s_at
mMC014746
Participates
as a component of
p-STAT2:STAT1:p-IFNAR1:p-TYK2 [plasma membrane] (Mus musculus)
p-IFNAR1:p-TYK2:SOCS-1/SOCS-3 [plasma membrane] (Mus musculus)
p-IFNAR1:p-TYK2 [plasma membrane] (Mus musculus)
STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Mus musculus)
p-STAT2:p-STAT1:p-IFNAR1:p-TYK2 [plasma membrane] (Mus musculus)
p-STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Mus musculus)
Other forms of this molecule
Ifnar1 [plasma membrane]
Ifnar1 [plasma membrane]
Inferred From
p-Y466,Y481-IFNAR1 [plasma membrane]
(Homo sapiens)
Modified Residues
Name
O4'-phospho-L-tyrosine at 466 (in Homo sapiens)
Coordinate
466
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 481 (in Homo sapiens)
Coordinate
481
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
NP_034638.2
Ensembl
ENSMUSG00000022967
,
ENSMUST00000117748
,
ENSMUST00000023689
,
ENSMUSP00000112670
,
ENSMUSP00000023689
PRO
P33896
MGI
107658
PDB
3WCY
HMDB Protein
HMDBP13843
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q60855
14
K48polyUb-RIPK1 [cytosol]
(R-MMU-6783308)
PolyUb-RIPK1 [cytosol]
(R-MMU-6783197)
RIPK1 [cytosol]
(R-MMU-168651)
K63polyUb-RIPK1 [cytosol]
(R-MMU-937021)
phospho-p-S166-RIPK1 [cytosol]
(R-MMU-5218872)
phospho-p-S357-RIPK1 [cytosol]
(R-MMU-9819116)
phospho-p-S320-RIPK1 [cytosol]
(R-MMU-9815498)
phospho-K63,M1polyUb, p-T189-RIPK1 [cytosol]
(R-MMU-9817377)
polyUb-K377,K604,K634-RIPK1 [cytosol]
(R-MMU-9818391)
RIPK1(325-671) [cytosol]
(R-MMU-5212671)
RIPK1(1-324) [cytosol]
(R-MMU-5212664)
K63,M1polyUb-RIPK1 [cytosol]
(R-MMU-9793681)
phospho-K63,Met1polyUb-p-S25-RIPK1 [cytosol]
(R-MMU-9818793)
K48polyUb-K571,K604,K627-RIPK1 [cytosol]
(R-MMU-9796639)
0.463
2
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