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Traf6 [plasma membrane]
Stable Identifier
R-MMU-936955
Type
Genes and Transcripts [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
plasma membrane
Synonyms
TRAF6, P70196
Locations in the PathwayBrowser
Expand all
Immune System (Mus musculus)
Innate Immune System (Mus musculus)
Toll-like Receptor Cascades (Mus musculus)
Toll Like Receptor 10 (TLR10) Cascade (Mus musculus)
MyD88 cascade initiated on plasma membrane (Mus musculus)
IRAK1 recruits IKK complex (Mus musculus)
IRAK1 phosphorylates Pellino (Mus musculus)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Mus musculus)
TRAF6:hp-IRAK1 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
Pellino binds hp-IRAK1:TRAF6 (Mus musculus)
TRAF6:hp-IRAK1 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Mus musculus)
TRAF6:hp-IRAK1 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
Pellino ubiquitinates hp-IRAK1 (Mus musculus)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Mus musculus)
TRAF6:hp-IRAK1 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
IRAK2 mediated activation of TAK1 complex (Mus musculus)
Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
p-IRAK2:oligo-TRAF6 [plasma membrane] (Mus musculus)
TRAF6:p-IRAK2 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
IRAK2 induces TRAF6 oligomerization (Mus musculus)
TRAF6:p-IRAK2 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
p-IRAK2:oligo-TRAF6 [plasma membrane] (Mus musculus)
TRAF6:p-IRAK2 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
Toll Like Receptor 2 (TLR2) Cascade (Mus musculus)
Toll Like Receptor TLR1:TLR2 Cascade (Mus musculus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Mus musculus)
IRAK1 recruits IKK complex (Mus musculus)
IRAK1 phosphorylates Pellino (Mus musculus)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Mus musculus)
TRAF6:hp-IRAK1 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
Pellino binds hp-IRAK1:TRAF6 (Mus musculus)
TRAF6:hp-IRAK1 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Mus musculus)
TRAF6:hp-IRAK1 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
Pellino ubiquitinates hp-IRAK1 (Mus musculus)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Mus musculus)
TRAF6:hp-IRAK1 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
IRAK2 mediated activation of TAK1 complex (Mus musculus)
Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
p-IRAK2:oligo-TRAF6 [plasma membrane] (Mus musculus)
TRAF6:p-IRAK2 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
IRAK2 induces TRAF6 oligomerization (Mus musculus)
TRAF6:p-IRAK2 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
p-IRAK2:oligo-TRAF6 [plasma membrane] (Mus musculus)
TRAF6:p-IRAK2 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
Toll Like Receptor TLR6:TLR2 Cascade (Mus musculus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Mus musculus)
IRAK1 recruits IKK complex (Mus musculus)
IRAK1 phosphorylates Pellino (Mus musculus)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Mus musculus)
TRAF6:hp-IRAK1 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
Pellino binds hp-IRAK1:TRAF6 (Mus musculus)
TRAF6:hp-IRAK1 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Mus musculus)
TRAF6:hp-IRAK1 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
Pellino ubiquitinates hp-IRAK1 (Mus musculus)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Mus musculus)
TRAF6:hp-IRAK1 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
IRAK2 mediated activation of TAK1 complex (Mus musculus)
Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
p-IRAK2:oligo-TRAF6 [plasma membrane] (Mus musculus)
TRAF6:p-IRAK2 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
IRAK2 induces TRAF6 oligomerization (Mus musculus)
TRAF6:p-IRAK2 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
p-IRAK2:oligo-TRAF6 [plasma membrane] (Mus musculus)
TRAF6:p-IRAK2 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
Toll Like Receptor 4 (TLR4) Cascade (Mus musculus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Mus musculus)
IRAK1 recruits IKK complex (Mus musculus)
IRAK1 phosphorylates Pellino (Mus musculus)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Mus musculus)
TRAF6:hp-IRAK1 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
Pellino binds hp-IRAK1:TRAF6 (Mus musculus)
TRAF6:hp-IRAK1 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Mus musculus)
TRAF6:hp-IRAK1 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
Pellino ubiquitinates hp-IRAK1 (Mus musculus)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Mus musculus)
TRAF6:hp-IRAK1 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
IRAK2 mediated activation of TAK1 complex (Mus musculus)
Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
p-IRAK2:oligo-TRAF6 [plasma membrane] (Mus musculus)
TRAF6:p-IRAK2 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
IRAK2 induces TRAF6 oligomerization (Mus musculus)
TRAF6:p-IRAK2 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
p-IRAK2:oligo-TRAF6 [plasma membrane] (Mus musculus)
TRAF6:p-IRAK2 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
Toll Like Receptor 5 (TLR5) Cascade (Mus musculus)
MyD88 cascade initiated on plasma membrane (Mus musculus)
IRAK1 recruits IKK complex (Mus musculus)
IRAK1 phosphorylates Pellino (Mus musculus)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Mus musculus)
TRAF6:hp-IRAK1 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
Pellino binds hp-IRAK1:TRAF6 (Mus musculus)
TRAF6:hp-IRAK1 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Mus musculus)
TRAF6:hp-IRAK1 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
Pellino ubiquitinates hp-IRAK1 (Mus musculus)
TRAF6:hp-IRAK1:Pellino [plasma membrane] (Mus musculus)
TRAF6:hp-IRAK1 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
IRAK2 mediated activation of TAK1 complex (Mus musculus)
Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
p-IRAK2:oligo-TRAF6 [plasma membrane] (Mus musculus)
TRAF6:p-IRAK2 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
IRAK2 induces TRAF6 oligomerization (Mus musculus)
TRAF6:p-IRAK2 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
p-IRAK2:oligo-TRAF6 [plasma membrane] (Mus musculus)
TRAF6:p-IRAK2 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
Traf6 [plasma membrane] (Mus musculus)
External Reference Information
External Reference
UniProt:P70196-2 Traf6
Gene Names
Traf6
Participates
as a component of
TRAF6:hp-IRAK1 [plasma membrane] (Mus musculus)
p-IRAK2:oligo-TRAF6 [plasma membrane] (Mus musculus)
TRAF6:p-IRAK2 [plasma membrane] (Mus musculus)
Other forms of this molecule
Traf6 [cytosol]
Traf6 [cytosol]
TNF receptor associated factor 6 isoform 2 [cytosol]
Traf6 [endosome membrane]
Traf6 [endosome membrane]
Traf6 [plasma membrane]
Traf6 [cytosol]
Traf6 [cytosol]
Inferred From
TRAF6 [plasma membrane]
(Homo sapiens)
Interactors (14)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P62991 UBIQ
0.835
5
UniProt:Q9QZH6
2
Ecsit [mitochondrial inner membrane]
(R-MMU-5689047)
Ecsit [cytosol]
(R-MMU-168064)
0.729
5
UniProt:P22366
1
Myd88 [cytosol]
(R-MMU-166059)
0.623
4
UniProt:Q61084
1
MAP3K3 [cytosol]
(R-MMU-507725)
0.589
5
UniProt:Q8C0E5 Q8C0E5
0.581
3
UniProt:Q8N7N6 CIKS
0.547
4
UniProt:Q8K4B2
1
IRAK3 [cytosol]
(R-MMU-166103)
0.547
3
UniProt:Q62227
1
Nr0b2 [nucleoplasm]
(R-MMU-376312)
0.537
5
UniProt:P17879
4
HSPA1A [nucleoplasm]
(R-MMU-6792605)
HSPA1A [extracellular region]
(R-MMU-6805872)
HSPA1A [ficolin-1-rich granule lumen]
(R-MMU-6801496)
HSPA1A [cytosol]
(R-MMU-6792602)
0.524
3
UniProt:Q9EQY0
2
phospho-p-S724-ERN1 [endoplasmic reticulum membrane]
(R-MMU-381029)
ERN1 [endoplasmic reticulum membrane]
(R-MMU-381076)
0.524
6
UniProt:Q793I8
2
Tifa [cytosol]
(R-MMU-451582)
phospho-Tifa [cytosol]
(R-MMU-9645512)
0.508
2
UniProt:P27512
1
Cd40 [plasma membrane]
(R-MMU-198117)
0.508
2
UniProt:O35305
1
TNFRSF11A [plasma membrane]
(R-MMU-5668756)
0.508
2
UniProt:Q96CG3 TIFA
2
TIFA [cytosol]
(R-HSA-451582)
p-T9-TIFA [cytosol]
(R-HSA-9645512)
0.499
4
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