Notch4 binds Smad3

Stable Identifier
R-MMU-9605444
Type
Reaction [binding]
Species
Mus musculus
Compartment
cytosol
General
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PNG
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 | PPTX  | SBGN
Notch4 binds Smad3

Endogenous mouse Notch4 intracellular domain fragment (NICD4) binds to endogenous mouse Smad3, phosphorylated in response to TGF-beta signaling (Sun et al. 2005).

Literature References
PubMed ID Title Journal Year
16007227 Notch4 intracellular domain binding to Smad3 and inhibition of the TGF-beta signaling

Sun, Y, Lowther, W, Kato, K, Bianco, C, Kenney, N, Strizzi, L, Raafat, D, Hirota, M, Khan, NI, Bargo, S, Jones, B, Salomon, D, Callahan, R

Oncogene 2005
Participants
Input
Output
Orthologous Events
NOTCH4 binds SMAD3 (Homo sapiens)
Authored
Orlic-Milacic, M  (2018-04-05)
Reviewed
Haw, R  (2018-05-01)
Created
Orlic-Milacic, M  (2018-04-11)