Btk autophosphorylates

Stable Identifier
R-MMU-9607033
Type
Reaction [transition]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Btk autophosphorylates

After phosphorylation on tyrosine-551 by Lyn or Syk, Btk autophosphorylates tyrosine-223 (Mahajan et al. 1995, Park et al. 1996).

Literature References
PubMed ID Title Journal Year
8630736 Regulation of Btk function by a major autophosphorylation site within the SH3 domain

Park, H, Wahl, MI, Afar, DE, Turck, CW, Rawlings, DJ, Tam, C, Scharenberg, AM, Kinet, JP, Witte, ON

Immunity 1996
7565679 Src family protein tyrosine kinases induce autoactivation of Bruton's tyrosine kinase

Mahajan, S, Fargnoli, J, Burkhardt, AL, Kut, SA, Saouaf, SJ, Bolen, JB

Mol. Cell. Biol. 1995
Participants
Catalyst Activity
Catalyst Activity
Title
protein tyrosine kinase activity of p-Y551-Btk [cytosol]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created
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