GluN1:GluN2B (Grin1:Grin2b) di-heterotetramers bind Lin7:Cask:Apba1 and Kif17

Stable Identifier
R-MMU-9610428
Type
Reaction [binding]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
GluN1:GluN2B (Grin1:Grin2b) di-heterotetramers bind Lin7:Cask:Apba1 and Kif17

In mouse neurons, GluN1:GluN2B (Grin1:Grin2b) di-heteromers are transported to the plasma membrane from the endoplasmic reticulum (ER) via transport vesicles. At the membrane of transport vesicles, GluN1:GluN2b NMDA receptors associate with the complex of Lin7 (Lin7a, Lin7b or Lin7c), Cask and Apba1. The microtubule-associated kinesin motor protein Kif17 binds to the Lin7:Cask:Apba1 complex (Jo et al. 1999, Setou et al. 2000).

Participants
Orthologous Events
Authored
Reviewed
Created