Reactome | Grin1 [transport vesicle membrane]

Grin1 [transport vesicle membrane]

Stable Identifier

R-MMU-9610566

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

transport vesicle membrane

Synonyms

Nr1, Glutamate receptor ionotropic, NMDA 1, NMDZ1_MOUSE

External Reference Information

External Reference

UniProt:P35438 Grin1

Gene Names

Grin1, Glurz1

Chain

signal peptide:1-18, chain:19-938

Reference Genes

BioGPS Gene:14810 Grin1

ENSEMBL:ENSMUSG00000026959 Grin1

KEGG Gene (Mus musculus):14810 Grin1

Monarch:14810 Grin1

NCBI Gene:14810 Grin1

UCSC:P35438 Grin1

Reference Transcript

Other Identifiers

104684_at

104685_g_at

104686_at

10480676

1437968_at

1450202_at

14810

17382496

4368570

4489597

4511966

4516839

4557172

4607922

4671453

4707601

4798850

4845037

5015388

5097532

5132395

5186466

5225395

5245451

5297320

5306877

5385704

5387456

5396483

5459569

5502910

5579913

5597149

A_52_P69292

A_55_P2033366

A_65_P18935

D10028_s_at

GE34519

GO:0003674

GO:0004970

GO:0005216

GO:0005575

GO:0006810

GO:0006811

GO:0007165

GO:0008150

GO:0015276

GO:0016020

GO:0022857

GO:0038023

ILMN_1253164

mMC020073

Participates

as a component of

Grin1:Grin2b di-heterotetramer [transport vesicle membrane] (Mus musculus)

Other forms of this molecule

Grin1 [plasma membrane]

Grin1 [endoplasmic reticulum membrane]

Cross References

RefSeq

NP_001171128.1, NP_032195.1, NP_001171127.1

Ensembl

ENSMUSP00000109951, ENSMUST00000028335, ENSMUSG00000026959, ENSMUSP00000028335, ENSMUST00000114312

PRO

P35438

MGI

95819

Interactors (88)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q62108 Dlg4	3	Dlg4 [endocytic vesicle membrane] (R-MMU-416847) SAP-90 [plasma membrane] (R-MMU-443606) Dlg4 [cytosol] (R-MMU-6794267)	0.926	16
UniProt:Q01097 Grin2b	7	phospho-Grin2b [plasma membrane] (R-MMU-3928477) p-Nr2b [plasma membrane] (R-MMU-3928470) Grin2b [endoplasmic reticulum membrane] (R-MMU-9610361) Grin2b [plasma membrane] (R-MMU-3928478) Grin2b [transport vesicle membrane] (R-MMU-9610571) Grin2b [endoplasmic reticulum membrane] (R-MMU-9609765) Grin2b [plasma membrane] (R-MMU-419558)	0.794	12
UniProt:P35436 Grin2a	2	Grin2a [plasma membrane] (R-MMU-9006562) Grin2a [endoplasmic reticulum membrane] (R-MMU-9609760)	0.723	8
UniProt:Q9D415	1	Dlgap1 [plasma membrane] (R-MMU-6794239)	0.723	6
UniProt:Q9QVP9	3	Ptk2b [cytosol] (R-MMU-390932) phospho-Ptk2b [cytosol] (R-MMU-508515) phospho-Ptk2b [cytosol] (R-MMU-5218721)	0.643	4
UniProt:P15116	3	Cdh2 [endoplasmic reticulum lumen] (R-MMU-8956761) phospho-Cdh2 [endoplasmic reticulum lumen] (R-MMU-8956899) Cdh2 [plasma membrane] (R-MMU-191429)	0.643	4
UniProt:Q62077 Plcg1	10	Plcg1 [cytosol] (R-MMU-9638030) p-Y-Plcg1 [cytosol] (R-MMU-9029083) p-4Y-Plcg1 [plasma membrane] (R-MMU-9030452) P-Plcg1 [cytosol] (R-MMU-1251936) Plcg1 [plasma membrane] (R-MMU-1251925) phospho-Plcg1 [plasma membrane] (R-MMU-1169084) phospho-Plcg1 [cytosol] (R-MMU-202357) Plcg1 [cytosol] (R-MMU-202320) Plcg1 [plasma membrane] (R-MMU-167682) phospho-Plcg1 [plasma membrane] (R-MMU-167679)	0.643	4
UniProt:P68369 Tuba1a	6	Tuba1a [axonemal microtubule] (R-MMU-5624852) Tuba1a [cytosol] (R-MMU-5618312) Tuba1a [cytosol] (R-MMU-8867428) Tuba1a [cytosol] (R-MMU-8867408) Tuba1a [axonemal microtubule] (R-MMU-5610433) Tubulin alpha-1A chain [cytosol] (R-MMU-2316296)	0.643	5
UniProt:Q99P24 Q99P24			0.643	4
UniProt:Q02248 Ctnnb1	12	phospho-Ctnnb1 [cytosol] (R-MMU-3134933) phospho-Ctnnb1 [nucleoplasm] (R-MMU-3134926) Ctnnb1 [plasma membrane] (R-MMU-9038440) Ctnnb1 [nucleoplasm] (R-MMU-3451168) Ctnnb1 [cytosol] (R-MMU-448839) Ctnnb1 [cytosol] (R-MMU-202930) Ctnnb1 [cytosol] (R-MMU-202950) phospho-Ctnnb1 [cytosol] (R-MMU-8942374) beta-catenin [cytosol] (R-MMU-206225) phospho-Ctnnb1 [cytosol] (R-MMU-8942369) phospho-Ctnnb1 [cytosol] (R-MMU-8942367) phospho-Ctnnb1 [cytosol] (R-MMU-8942363)	0.643	4
UniProt:P31324	2	Prkar2b [cytosol] (R-MMU-57842) Prkar2b [ciliary base] (R-MMU-5610414)	0.643	4
UniProt:Q63844 Mapk3	7	Phospho-ERK1 [nucleoplasm] (R-MMU-198664) phospho-Mapk3 [cytosol] (R-MMU-9635775) phospho-Mapk3 [cytosol] (R-MMU-2422448) Mapk3 [nucleoplasm] (R-MMU-73724) phospho-Mapk3 [cytosol] (R-MMU-109842) Mapk3 [cytosol] (R-MMU-59284) phospho-Mapk3 [nucleoplasm] (R-MMU-112359)	0.643	4
UniProt:P46460	1	Nsf [cytosol] (R-MMU-264471)	0.643	5
UniProt:Q9Z0J4	1	Nos1 [cytosol] (R-MMU-419293)	0.643	4
UniProt:P16054	2	phospho-Prkce [plasma membrane] (R-MMU-198260) Prkce [cytosol] (R-MMU-58202)	0.643	4
UniProt:P63318	1	Prkcg [cytosol] (R-MMU-58204)	0.643	4
UniProt:P39053	3	Dnm1 [cytosol] (R-MMU-2213182) Dnm1 [lysosomal membrane] (R-MMU-196150) Dnm1 [plasma membrane] (R-MMU-177488)	0.643	5
UniProt:P05480 Src	12	phospho-Src [cytosol] (R-MMU-377592) Src [cytosol] (R-MMU-191648) phospho-Src [plasma membrane] (R-MMU-1810408) Src [plasma membrane] (R-MMU-65043) phospho-Src [plasma membrane] (R-MMU-377598) Src [cytosol] (R-MMU-418782) phospho-Src [plasma membrane] (R-MMU-112331) Src [plasma membrane] (R-MMU-8876922) MyrG-p-Y424-Src [plasma membrane] (R-MMU-9011258) Activated Src [nucleoplasm] (R-MMU-8937700) phospho-Src [cytosol] (R-MMU-8964276) Src [cytosol] (R-MMU-9628701)	0.643	4
UniProt:Q62261 Sptbn1	2	Sptbn1 [cytosol] (R-MMU-420048) Sptbn1 [cytosol] (R-MMU-9662390)	0.643	4
UniProt:Q80Z38	1	Shank2 [cytosol] (R-MMU-6794265)	0.643	4
UniProt:P60710 Actb	4	Actb [nucleoplasm] (R-MMU-3321990) Actb [lysosomal membrane] (R-MMU-196160) Actin, cytoplasmic 1 [cytosol] (R-MMU-2263470) Actb [plasma membrane] (R-MMU-196016)	0.643	4
UniProt:Q61495	5	Dsg1a [ficolin-1-rich granule membrane] (R-MMU-6801298) Dsg1a [cornified envelope] (R-MMU-8847719) Dsg1a [cytosol] (R-MMU-202921) Dsg1a [plasma membrane] (R-MMU-202922) Dsg1a [plasma membrane] (R-MMU-202912)	0.643	4
UniProt:P18654 Rps6ka3	5	p-S227-Rps6ka3 [nucleoplasm] (R-MMU-9620027) phospho-Rps6ka3 [nucleoplasm] (R-MMU-199830) Rps6ka3 [nucleoplasm] (R-MMU-9620028) phospho-Rps6ka3 [cytosol] (R-MMU-9619872) phospho-Rps6ka3 [nucleoplasm] (R-MMU-444286)	0.643	4
UniProt:P11627 L1cam	6	phospho-L1cam [plasma membrane] (R-MMU-444982) phospho-L1cam [plasma membrane] (R-MMU-392737) L1_MOUSE [plasma membrane] (R-MMU-443603) phospho-L1cam [plasma membrane] (R-MMU-444985) phospho-L1cam [plasma membrane] (R-MMU-444980) L1cam [plasma membrane] (R-MMU-191465)	0.643	4
UniProt:Q8BFV3	1	Dusp4 [nucleoplasm] (R-MMU-203794)	0.643	4
UniProt:P31938 Map2k1	5	Mek1 [cytosol] (R-MMU-451658) phospho-Map2k1 [cytosol] (R-MMU-5674490) phospho-Map2k1 [cytosol] (R-MMU-112374) phospho-Map2k1 [cytosol] (R-MMU-112339) Phospho Mek1 [cytosol] (R-MMU-451693)	0.643	4
UniProt:P28652 Camk2b	6	p-T287-Camk2b [nucleoplasm] (R-MMU-9608171) phospho-Camk2b [plasma membrane] (R-MMU-432791) phospho-Camk2b [nucleoplasm] (R-MMU-444787) phospho-Camk2b [endocytic vesicle membrane] (R-MMU-417009) Camk2b [cytosol] (R-MMU-9611360) phospho-Camk2b [cytosol] (R-MMU-445371)	0.643	5
UniProt:P47713	4	phospho-Pla2g4a [endoplasmic reticulum membrane] (R-MMU-111859) Pla2g4a [endoplasmic reticulum membrane] (R-MMU-934669) Pla2g4a [mitochondrial inner membrane] (R-MMU-1524099) Pla2g4a [cytosol] (R-MMU-378502)	0.643	4
UniProt:P97772	1	Grm1 [plasma membrane] (R-MMU-420521)	0.643	4
UniProt:Q9Z2Y3	1	Homer1 [cytosol] (R-MMU-6794264)	0.643	4
UniProt:P17879	4	Hspa1b [nucleoplasm] (R-MMU-6792605) Hspa1b [cytosol] (R-MMU-6792602) Hspa1b [extracellular region] (R-MMU-6805872) Hspa1b [ficolin-1-rich granule lumen] (R-MMU-6801496)	0.643	5
UniProt:P68404	5	Prkcb [cytosol] (R-MMU-58198) Prkcb [plasma membrane] (R-MMU-156467) phospho-Prkcb [cytosol] (R-MMU-5218706) phospho-Prkcb [cytosol] (R-MMU-5218728) phospho-Prkcb [nucleoplasm] (R-MMU-5223294)	0.643	4
UniProt:Q60676	2	Ppp5c [nucleoplasm] (R-MMU-5683410) Ppp5c [cytosol] (R-MMU-5675402)	0.643	4
UniProt:P20357 MTAP2			0.643	4
UniProt:P39087	2	Grik2 [plasma membrane] (R-MMU-450192) Grik2 [plasma membrane] (R-MMU-451318)	0.643	4
UniProt:Q9JI91	3	Actn2 [platelet alpha granule lumen] (R-MMU-349727) Actn2 [extracellular region] (R-MMU-349725) Actn2 [cytosol] (R-MMU-390562)	0.643	5
UniProt:Q60598 Cttn	3	Cttn [cytosol] (R-MMU-442836) p-S113-Cttn [cytosol] (R-MMU-442839) Cttn [cytosol] (R-MMU-201894)	0.643	4
UniProt:P70175 Dlg3	3	Dlg3 [plasma membrane] (R-MMU-443586) Dlg3 [cytosol] (R-MMU-6794232) Dlg3 [plasma membrane] (R-MMU-443609)	0.643	5
UniProt:P63085 Mapk1	9	phospho-Mapk1 [cytosol] (R-MMU-109853) phospho-Mapk1 [nucleoplasm] (R-MMU-112354) Mapk1 [cytosol] (R-MMU-59282) Mapk1 [nucleoplasm] (R-MMU-199960) Phospho-ERK2 [nucleoplasm] (R-MMU-198682) phospho-Mapk1 [cytosol] (R-MMU-9635773) Mapk1 [azurophil granule lumen] (R-MMU-6799225) Mapk1 [extracellular region] (R-MMU-6806250) Mapk1 [ficolin-1-rich granule lumen] (R-MMU-6800964)	0.643	4
UniProt:Q63932	3	phospho-Map2k2 [cytosol] (R-MMU-169292) Map2k2 [cytosol] (R-MMU-59504) phospho-Map2k2 [cytosol] (R-MMU-109848)	0.643	4
UniProt:Q99N57	10	phospho-Raf1 [plasma membrane] (R-MMU-5672665) phospho-Raf1 [cytosol] (R-MMU-5672664) phospho-Raf1 [cytosol] (R-MMU-206028) phospho-Raf1 [plasma membrane] (R-MMU-5675193) phospho-Raf1 [cytosol] (R-MMU-109786) phospho-Raf1 [plasma membrane] (R-MMU-5675420) phospho-Raf1 [plasma membrane] (R-MMU-206222) phospho-Raf1 [cytosol] (R-MMU-5624469) phospho-Raf1 [cytosol] (R-MMU-5624465) Raf1 [cytosol] (R-MMU-167205)	0.643	4
UniProt:P63001 Rac1	7	Rac1 [ficolin-1-rich granule membrane] (R-MMU-6804802) Rac1 [secretory granule membrane] (R-MMU-6804770) Rac1 [plasma membrane] (R-MMU-2316446) Rac1 [endoplasmic reticulum membrane] (R-MMU-5672076) Rac1 [plasma membrane] (R-MMU-2316449) Rac1 [cytosol] (R-MMU-442615) Rac1 [plasma membrane] (R-MMU-421093)	0.643	4
UniProt:Q99104 Myo5a	3	Myo5a [cytosol] (R-MMU-216848) p-S1650-Myo5a [cytosol] (R-MMU-1449612) Myo5a [cytosol] (R-MMU-1428499)	0.643	5
UniProt:P35235 Ptpn11	5	Ptpn11 [cytosol] (R-MMU-210002) p-Y546,Y584-Shp2 [cytosol] (R-MMU-443116) Ptpn11 [nucleoplasm] (R-MMU-8937745) phospho-Ptpn11 [cytosol] (R-MMU-162573) Ptpn11 [cytosol] (R-MMU-162563)	0.643	4
UniProt:Q80ZJ1 RAP2A			0.643	4
UniProt:P63328 Ppp3ca	2	Ppp3ca [cytosol] (R-MMU-2025986) Ppp3ca [nucleoplasm] (R-MMU-2685599)	0.643	5
UniProt:Q04690	2	Nf1 [cytosol] (R-MMU-947770) Nf1 [cytosol] (R-MMU-5658418)	0.643	4
UniProt:Q91XM9	2	Dlg2 [plasma membrane] (R-MMU-9610662) Dlg2 [cytosol] (R-MMU-6794230)	0.643	5
UniProt:Q9WV31 ARC			0.643	4
UniProt:P49025 Cit	3	Cit [cytosol] (R-MMU-5625896) Cit [cytosol] (R-MMU-5671976) Cit [cytosol] (R-MMU-1629806)	0.643	4
UniProt:P62204 CALM			0.643	4
UniProt:P11798 Camk2a	6	p-T286-Camk2a [nucleoplasm] (R-MMU-9608160) phospho-Camk2a [plasma membrane] (R-MMU-432796) phospho-Camk2a [endocytic vesicle membrane] (R-MMU-416999) phospho-Camk2a [cytosol] (R-MMU-4332334) phospho-Camk2a [cytosol] (R-MMU-445368) Camk2a [cytosol] (R-MMU-4332329)	0.597	4
UniProt:Q9Z1B3 Plcb1	2	Plcb1 [cytosol] (R-MMU-61693) 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1 [plasma membrane] (R-MMU-445858)	0.527	2
UniProt:P42337 Pik3ca	1	Pik3ca [cytosol] (R-MMU-9027214)	0.462	2
UniProt:P12367 Prkar2a	3	Prkar2a [ciliary base] (R-MMU-5610412) Prkar2a [cytosol] (R-MMU-9010721) Prkar2a [cytosol] (R-MMU-57840)	0.462	2
UniProt:Q6Q476 Q6Q476			0.462	2
UniProt:P12849	2	Prkar1b [cytosol] (R-MMU-57838) Prkar1b [ciliary base] (R-MMU-5610409)	0.462	2
UniProt:Q9DBC7	2	Prkar1a [cytosol] (R-MMU-57836) Prkar1a [ciliary base] (R-MMU-5610408)	0.462	2
UniProt:P06837	2	Gap43 [plasma membrane] (R-MMU-8933482) Gap43 [plasma membrane] (R-MMU-452888)	0.462	2
UniProt:Q9ERK4 XPO2			0.462	2
UniProt:P54830 PTN5			0.462	2
UniProt:P46735 MYO1B			0.462	3
UniProt:P62827	2	Ran [cytosol] (R-MMU-165540) Ran [nucleoplasm] (R-MMU-165528)	0.462	2
UniProt:Q68FD5	6	Cltc [cytosol] (R-MMU-350824) Cltc [lysosomal membrane] (R-MMU-2980660) Cltc [trans-Golgi network membrane] (R-MMU-2130474) Cltc [endolysosome membrane] (R-MMU-8870827) Cltc [clathrin-coated endocytic vesicle membrane] (R-MMU-5138450) Cltc [plasma membrane] (R-MMU-2980668)	0.462	3
UniProt:O35526 Stx1a	3	Syntaxin-1A [plasma membrane] (R-MMU-216884) Stx1a [cytosol] (R-MMU-9609866) Stx1a [plasma membrane] (R-MMU-449128)	0.462	2
UniProt:P62259 Ywhae	1	14-3-3 epsilon [cytosol] (R-MMU-1445119)	0.462	2
UniProt:Q61411 Hras	8	Hras [Golgi membrane] (R-MMU-9647896) Hras [plasma membrane] (R-MMU-9665052) Hras [cytosol] (R-MMU-9647765) Hras [endoplasmic reticulum membrane] (R-MMU-9647918) Hras [endoplasmic reticulum membrane] (R-MMU-9647796) Hras [endoplasmic reticulum membrane] (R-MMU-9647788) Hras [plasma membrane] (R-MMU-1250504) Hras [plasma membrane] (R-MMU-9647912)	0.462	2
UniProt:Q61337 Bad	6	Bad [mitochondrial outer membrane] (R-MMU-114242) phospho-Bad [cytosol] (R-MMU-217297) p-S136-Bad [cytosol] (R-MMU-3139049) Bad [cytosol] (R-MMU-3139043) Bad [cytosol] (R-MMU-50662) phospho-Bad [cytosol] (R-MMU-198335)	0.462	2
UniProt:P62492 Rab11a	4	Rab11a [cytosol] (R-MMU-8873781) Rab11a [recycling endosome membrane] (R-MMU-2029023) Rab11a [cytosol] (R-MMU-5623395) GGC-Rab11a [cytoplasmic vesicle membrane] (R-MMU-1458553)	0.462	2
UniProt:P68040	1	Rack1 [cytosol] (R-MMU-5626956)	0.462	2
UniProt:Q9WV60 Gsk3b	3	Gsk3b [cytosol] (R-MMU-2997551) GSK3beta [cytosol] (R-MMU-206095) Gsk3b [nucleoplasm] (R-MMU-182565)	0.462	2
UniProt:O08638	1	Myh11 [cytosol] (R-MMU-420855)	0.462	3
UniProt:P05132 Prkaca	4	Prkaca [ciliary base] (R-MMU-5610402) mPKA alpha subunit [nucleoplasm] (R-MMU-164105) Prkaca [cytosol] (R-MMU-163497) Prkaca [nucleoplasm] (R-MMU-9005852)	0.462	2
UniProt:Q8R071	1	Itpka [cytosol] (R-MMU-1604604)	0.462	2
UniProt:P63330	4	Ppp2ca [nucleoplasm] (R-MMU-8857791) phospho-Ppp2ca [cytosol] (R-MMU-8857939) Ppp2ca [nucleoplasm] (R-MMU-165978) Ppp2ca [cytosol] (R-MMU-165971)	0.462	2
UniProt:P63011 Rab3a	9	Rab3a [cytosol] (R-MMU-8870429) Rab3a [secretory granule membrane] (R-MMU-8875319) Rab3a [cytosol] (R-MMU-8870410) Rab3a [clathrin-sculpted acetylcholine transport vesicle membrane] (R-MMU-379365) Rab3a [clathrin-sculpted glutamate transport vesicle membrane] (R-MMU-9664098) Rab3a [secretory granule membrane] (R-MMU-6804968) Rab3a [clathrin-sculpted monoamine transport vesicle membrane] (R-MMU-372512) Rab3a [plasma membrane] (R-MMU-210461) Rab3a [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-MMU-917743)	0.462	2
UniProt:P35821 Ptpn1	2	Ptpn1 [cytosol] (R-MMU-210625) Ptp1b [cytosol] (R-MMU-210624)	0.462	2
UniProt:O55100	2	Syngr1 [azurophil granule membrane] (R-MMU-6799352) Syngr1 [plasma membrane] (R-MMU-6806271)	0.462	2
UniProt:Q8CBH3 Q8CBH3			0.462	2
UniProt:Q8K2I5 Q8K2I5			0.462	2
UniProt:Q9ERI2	5	Rab27a [cytosol] (R-MMU-8870427) Rab27a [melanosome membrane] (R-MMU-8877281) Rab27a [cytosol] (R-MMU-3008674) Rab27a [extracellular region] (R-MMU-6799682) Rab27a [specific granule lumen] (R-MMU-6799609)	0.462	2
UniProt:P61982 Ywhag	1	14-3-3 gamma [cytosol] (R-MMU-1445103)	0.462	2
UniProt:Q8VDD5 Myh9	1	Myh9 [cytosol] (R-MMU-1449615)	0.462	3
UniProt:P63321 Rala	1	GGC-Rala [cytoplasmic vesicle membrane] (R-MMU-1458486)	0.462	2
UniProt:P35438 Grin1	3	Grin1 [endoplasmic reticulum membrane] (R-MMU-9610359) Grin1 [plasma membrane] (R-MMU-3928395) Grin1 [transport vesicle membrane] (R-MMU-9610566)	0.462	2
UniProt:P63087	1	Ppp1cc [cytosol] (R-MMU-163443)	0.462	2
UniProt:P68181 Prkacb	3	Prkacb [cytosol] (R-MMU-163468) Prkacb [ciliary base] (R-MMU-5610404) Prkacb [nucleoplasm] (R-MMU-111937)	0.462	2
UniProt:Q61879 Myh10	2	Myh10 [cytosol] (R-MMU-419174) Myh10 [cytosol] (R-MMU-593678)	0.462	3

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