Phospho-Stat3 binds the promoter of the Cebpb gene

Stable Identifier
R-MMU-9617215
Type
Reaction
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Phospho-Stat3 binds the promoter of the Cebpb gene

Stat3 that is phosphorylated in response to Csf3 (G-CSF) binds an IL-6 RE II site located 1180 bp upstream of the start of transcription in the promoter of the Cebpb gene (Zhang et al. 2010). Transcription of Cebpb is activated during "emergency granulopoiesis" by cytokines produced in response to bacterial infection.

Literature References
PubMed ID Title Journal Year
20581311 STAT3 controls myeloid progenitor growth during emergency granulopoiesis

Zhang, H, Nguyen-Jackson, H, Panopoulos, AD, Li, HS, Murray, PJ, Watowich, SS

Blood 2010
Participants
Orthologous Events
Authored
Reviewed
Created
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