Reactome | Prnp [cytosol]

Prnp [cytosol]

Stable Identifier

R-MMU-9617597

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

PRNP, P04925

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P04925 Prnp

Gene Names

Prnp, Prn-p, Prp

Chain

signal peptide:1-22, chain:23-230, propeptide:231-254

Reference Genes

BioGPS Gene:19122 Prnp

ENSEMBL:ENSMUSG00000079037 Prnp

KEGG Gene (Mus musculus):19122 Prnp

Monarch:19122 Prnp

NCBI Gene:19122 Prnp

UCSC:P04925 Prnp

Reference Transcript

Other Identifiers

100606_at

10476314

1416130_at

1448233_at

17376541

19122

4626526

4743506

4938269

5227959

A_51_P483280

GE40543

GO:0005575

GO:0008150

GO:0016020

GO:0022607

GO:0051260

GO:0065003

ILMN_2619316

m13685_s_at

mMC025621

Participates

as a member of

Mislocalized membrane protein [cytosol] (Mus musculus)

Other forms of this molecule

Major prion protein [plasma membrane]

Inferred From

PRNP [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001265185.1, NP_035300.1

Ensembl

ENSMUST00000091288, ENSMUSP00000088833, ENSMUSG00000079037

ZINC target

P04925

PRO

P04925

ZINC - Predictions - Purchasable

PRIO_MOUSE

MGI

97769

PDB

6AQ7, 2KFM, 2L1K, 4H88, 1Y16, 6HHD, 1Y15, 4J8R, 1AG2, 3NVG, 2L1E, 4MA7, 2KU6, 2L39, 2K5O, 2L40, 2L1H, 2KFO, 4MA8, 6HER, 2L1D, 1XYX, 2KU5, 3NVH

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P04925 Prnp	2	Prnp [cytosol] (R-MMU-9617597) Major prion protein [plasma membrane] (R-MMU-420340)	0.957	17
UniProt:P12023-PRO_0000000118 APP			0.623	2
UniProt:Q60631 Grb2	3	Grb2 [plasma membrane] (R-MMU-202993) Grb2 [cytosol] (R-MMU-74686) Grb2 [cytosol] (R-MMU-443287)	0.618	7
UniProt:Q9QUG3	2	Prnd [plasma membrane] (R-MMU-8940803) Prnd [extracellular region] (R-MMU-8941074)	0.463	2

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