Cebpb and phospho-Stat3 bind the promoter of the Myc gene

Stable Identifier
R-MMU-9618581
Type
Reaction
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Cebpb and phospho-Stat3 bind the promoter of the Myc gene

Activated (phosphorylated) Stat3 activates transcription of Cebpb and both phospho-Stat3 and Cebpb bind the promoter of the Myc gene (Zhang et al. 2010). The expression of Myc enhances proliferation of myeloid progenitors during emergency granulopoiesis in response to bacterial infection.

Literature References
PubMed ID Title Journal Year
20581311 STAT3 controls myeloid progenitor growth during emergency granulopoiesis

Zhang, H, Nguyen-Jackson, H, Panopoulos, AD, Li, HS, Murray, PJ, Watowich, SS

Blood 2010
Participants
Orthologous Events
Authored
Reviewed
Created
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