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phospho-Rps6ka3 [cytosol]
Stable Identifier
R-MMU-9619872
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
p-S227,T365,S369,S386,T577,T737-RPS6KA3, P18654
Locations in the PathwayBrowser
Expand all
Neuronal System (Mus musculus)
Transmission across Chemical Synapses (Mus musculus)
Neurotransmitter receptors and postsynaptic signal transmission (Mus musculus)
Activation of NMDA receptors and postsynaptic events (Mus musculus)
Post NMDA receptor activation events (Mus musculus)
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling (Mus musculus)
RSK activation (Mus musculus)
p-S363,S380,T573 RS6K translocates to the nucleus (Mus musculus)
p-S221,T359.S363,S380,T573,T732-RSK [cytosol] (Mus musculus)
phospho-Rps6ka3 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:P18654 Rps6ka3
Gene Names
Rps6ka3, Mapkapk1b, Rps6ka-rs1, Rsk2
Chain
chain:1-740
Reference Genes
BioGPS Gene:110651 Rps6ka3
ENSEMBL:ENSMUSG00000031309 Rps6ka3
KEGG Gene (Mus musculus):110651 Rps6ka3
Monarch:110651 Rps6ka3
NCBI Gene:110651 Rps6ka3
UCSC:P18654 Rps6ka3
Reference Transcript
RefSeq:NM_148945.2 Rps6ka3
Other Identifiers
10602772
110651
132772_at
1427299_at
1452383_at
1455206_at
17539125
4343935
4450304
4488517
4536177
4540649
4557139
4601671
4649370
4678412
4720062
4725163
4766516
4899727
4923620
4962261
4972316
5000388
5003437
5006514
5011894
5088194
5092530
5099053
5107619
5143435
5149264
5149270
5221520
5264120
5300846
5313691
5340353
5355484
5356620
5363005
5367264
5373330
5427306
5448089
5499506
5532177
5545072
5548593
5549086
5567050
5599281
5600819
A_52_P283628
A_52_P75975
A_55_P1952981
A_55_P2404434
GE136378
GO:0000166
GO:0000287
GO:0002224
GO:0003674
GO:0004672
GO:0004674
GO:0004711
GO:0005515
GO:0005524
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005737
GO:0006464
GO:0006468
GO:0006915
GO:0007049
GO:0007165
GO:0008150
GO:0008219
GO:0009058
GO:0016301
GO:0016310
GO:0016740
GO:0019899
GO:0019901
GO:0030234
GO:0032496
GO:0034641
GO:0035556
GO:0043027
GO:0043154
GO:0043167
GO:0043226
GO:0045944
ILMN_1247009
ILMN_2505442
ILMN_2731080
Msa.6343.0_s_at
aa175340_s_at
mMC007499
mMC010680
Participant Of
hasMember
p-S221,T359.S363,S380,T573,T732-RSK [cytosol]
Other forms of this molecule
phospho-Rps6ka3 [nucleoplasm]
p-S227-Rps6ka3 [nucleoplasm]
Rps6ka3 [nucleoplasm]
phospho-Rps6ka3 [nucleoplasm]
Inferred From
p-S227,T365,S369,S386,T577,T737-RPS6KA3 [cytosol] (Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 227
Coordinate
227
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 365 (in Homo sapiens)
Coordinate
365
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at 369 (in Homo sapiens)
Coordinate
369
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 386 (in Homo sapiens)
Coordinate
386
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 577 (in Homo sapiens)
Coordinate
577
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-threonine at 737 (in Homo sapiens)
Coordinate
737
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
NP_683747.1
Ensembl
ENSMUSG00000031309
,
ENSMUST00000033671
,
ENSMUSP00000033671
PRO
P18654
MGI
104557
PDB
4GUE
,
3UBD
,
4EL9
,
5O1S
,
2QR8
,
3G51
,
4M8T
,
4MAO
,
2QR7
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P35438 Grin1
3
Grin1 [endoplasmic reticulum membrane]
(R-MMU-9610359)
Grin1 [plasma membrane]
(R-MMU-3928395)
Grin1 [transport vesicle membrane]
(R-MMU-9610566)
0.643
4
UniProt:P97879
2
Grip1 [cytosol]
(R-RNO-416633)
Grip1 [plasma membrane]
(R-RNO-416638)
0.581
3
UniProt:Q9WV48 Shank1
2
Shank1 [cytosol]
(R-RNO-6794274)
Shank1 [cytosol]
(R-RNO-6794229)
0.508
2
UniProt:Q4L1J4 MAGI1
0.508
2
UniProt:Q9JLU4 Shank3
2
Shank3 [cytosol]
(R-RNO-6794277)
Shank3 [cytosol]
(R-RNO-6794258)
0.508
2
UniProt:P28223-1 HTR2A
0.508
2
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