Pomc gene expression is inhibited by Foxo1

Stable Identifier
R-MMU-9623076
Type
Reaction [omitted]
Species
Mus musculus
Compartment
ReviewStatus
5/5
General
SVG |   | PPTX  | SBGN
Pomc gene expression is inhibited by Foxo1
In mouse hypothalamic neurons, Foxo1 directly inihibits transcription from the Pomc gene promoter, encoding Pro-opiomelanocortin (Kitamura et al. 2006).
Literature References
PubMed ID Title Journal Year
16604086 Forkhead protein FoxO1 mediates Agrp-dependent effects of leptin on food intake

Rossetti, L, Barsh, GS, Accili, D, Chua, SC, Kitamura, T, Xu, AW, Kitamura, YI, Feng, Y

Nat. Med. 2006
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This event is regulated
Orthologous Events
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