Foxo1 binds Ppargc1a

Stable Identifier
R-MMU-9623232
Type
Reaction [binding]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Foxo1 binds Ppargc1a

Mouse Foxo1 forms a complex with mouse Ppargc1a (Pgc-1alpha). Binding of Foxo1 to Ppargc1a is inhibited by Akt-mediated phosphorylation of Foxo1 (Puigserver et al. 2003).

Literature References
PubMed ID Title Journal Year
12754525 Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction

Puigserver, P, Rhee, J, Donovan, J, Walkey, CJ, Yoon, JC, Oriente, F, Kitamura, Y, Altomonte, J, Dong, H, Accili, D, Spiegelman, BM

Nature 2003
Participants
Orthologous Events
Authored
Reviewed
Created