Dmrt1 binds the Sox9 gene

Stable Identifier
R-MMU-9692268
Type
Reaction [binding]
Species
Mus musculus
Compartment
nucleoplasm
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Dmrt1 binds the Sox9 gene
Dmrt1, a direct target of Sox9, binds the promoter of the Sox9 gene (Matson et al. 2011, Lindeman et al. 2015). Dmrt1 and Sox9 are responsible for maintaining expression of Sox9 after Sox is initially activated by Sry (Matson et al. 2011).
Literature References
PubMed ID Title Journal Year
25683803 Sexual cell-fate reprogramming in the ovary by DMRT1

Zarkower, D, Gearhart, MD, Krentz, AD, Bardwell, VJ, Minkina, A, Lindeman, RE

Curr. Biol. 2015
21775990 DMRT1 prevents female reprogramming in the postnatal mammalian testis

Matson, CK, Zarkower, D, Griswold, MD, Sarver, AL, Bardwell, VJ, Murphy, MW

Nature 2011
Participants
Input
Output
Orthologous Events
DMRT1 binds the SOX9 gene (Homo sapiens)
Authored
May, B  (2020-06-22)
Reviewed
Imaimatsu, K  (2020-10-29)
Kanai, Y  (2020-10-29)
Created
May, B  (2020-06-22)
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