ThioTEPA produces interstrand crosslinks in mouse DNA

Stable Identifier
R-MMU-9750097
Type
Reaction [omitted]
Species
Mus musculus
Compartment
nucleoplasm
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
ThioTEPA produces interstrand crosslinks in mouse DNA
ThioTEPA produces DNA interstrand crosslinks in mouse leukemic cell line L1210 (Cohen et al. 1991).
Literature References
PubMed ID Title Journal Year
1714342 Interaction of N,N',N''-triethylenethiophosphoramide and N,N',N''-triethylenephosphoramide with cellular DNA

Wietharn, BE, Ross, DD, Pan, SS, Egorin, MJ, Ashar, B, Cohen, NA, Hilton, J, Snyder, SW

Cancer Res 1991
Participants
Input
Output
Orthologous Events
Anti-cancer drugs generate DNA interstrand crosslinks (Homo sapiens)
Authored
Orlic-Milacic, M  (2021-02-01)
Reviewed
Kadambat Nair, S  (2021-07-28)
Created
Orlic-Milacic, M  (2021-08-09)
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