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Uramustine produces interstrand crosslinks in mouse DNA
Stable Identifier
R-MMU-9750281
Type
Reaction [omitted]
Species
Mus musculus
Compartment
nucleoplasm
ReviewStatus
5/5
General
SBML
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BioPAX
Level 2
Level 3
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PDF
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SBGN
Uramustine produces DNA interstrand crosslinks in mouse leukemic cell line L1210 (O'Connor and Kohn 1990).
Literature References
PubMed ID
Title
Journal
Year
2265064
Comparative pharmacokinetics of DNA lesion formation and removal following treatment of L1210 cells with nitrogen mustards
Kohn, KW
,
O'Connor, PM
Cancer Commun
1990
Participants
Input
dsDNA [nucleoplasm]
(Mus musculus)
uramustine [nucleoplasm]
Output
ICL-DNA [nucleoplasm]
(Mus musculus)
Orthologous Events
Anti-cancer drugs generate DNA interstrand crosslinks (Homo sapiens)
Authored
Orlic-Milacic, M (2021-02-01)
Reviewed
Kadambat Nair, S (2021-07-28)
Created
Orlic-Milacic, M (2021-08-11)
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