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Cul3 [cytosol]
Stable Identifier
R-MMU-975979
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
CUL3, Q9JLV5
Locations in the PathwayBrowser
Expand all
Immune System (Mus musculus)
Adaptive Immune System (Mus musculus)
Class I MHC mediated antigen processing & presentation (Mus musculus)
Antigen processing: Ubiquitination & Proteasome degradation (Mus musculus)
Interaction of E3 with substrate and E2-Ub complex (Mus musculus)
Ag-substrate:E3:E2:Ub [cytosol] (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
RBX1:CUL3:BTB [cytosol] (Mus musculus)
Cul3 [cytosol] (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
RBX1:CUL3:BTB [cytosol] (Mus musculus)
Cul3 [cytosol] (Mus musculus)
Polyubiquitination of substrate (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
RBX1:CUL3:BTB [cytosol] (Mus musculus)
Cul3 [cytosol] (Mus musculus)
E3:K48-polyubiquitinated substrate [cytosol] (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
RBX1:CUL3:BTB [cytosol] (Mus musculus)
Cul3 [cytosol] (Mus musculus)
E3:Ub:substrate [cytosol] (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
RBX1:CUL3:BTB [cytosol] (Mus musculus)
Cul3 [cytosol] (Mus musculus)
Release of E3 from polyubiquitinated substrate (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
RBX1:CUL3:BTB [cytosol] (Mus musculus)
Cul3 [cytosol] (Mus musculus)
E3:K48-polyubiquitinated substrate [cytosol] (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
RBX1:CUL3:BTB [cytosol] (Mus musculus)
Cul3 [cytosol] (Mus musculus)
Transfer of Ub from E2 to substrate and release of E2 (Mus musculus)
Ag-substrate:E3:E2:Ub [cytosol] (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
RBX1:CUL3:BTB [cytosol] (Mus musculus)
Cul3 [cytosol] (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
RBX1:CUL3:BTB [cytosol] (Mus musculus)
Cul3 [cytosol] (Mus musculus)
E3:Ub:substrate [cytosol] (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
RBX1:CUL3:BTB [cytosol] (Mus musculus)
Cul3 [cytosol] (Mus musculus)
Metabolism of proteins (Mus musculus)
Post-translational protein modification (Mus musculus)
Neddylation (Mus musculus)
AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex (Mus musculus)
NEDD8-AcM-UBE2M:CRL3 E3 ubiquitin ligase :DCUN1D1,2,4,5 [cytosol] (Mus musculus)
CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Mus musculus)
RBX1:CUL3:BTB [cytosol] (Mus musculus)
Cul3 [cytosol] (Mus musculus)
CAND1 binds cytosolic CRL E3 ubiquitin ligases (Mus musculus)
CRL E3 ubiquitin ligase:CAND1 [cytosol] (Mus musculus)
CRL E3 ubiquitin ligases [cytosol] (Mus musculus)
RBX1:CUL3:BTB [cytosol] (Mus musculus)
Cul3 [cytosol] (Mus musculus)
CRL E3 ubiquitin ligases [cytosol] (Mus musculus)
RBX1:CUL3:BTB [cytosol] (Mus musculus)
Cul3 [cytosol] (Mus musculus)
COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Mus musculus)
CRL E3 ubiquitin ligase:CAND1 [cytosol] (Mus musculus)
CRL E3 ubiquitin ligases [cytosol] (Mus musculus)
RBX1:CUL3:BTB [cytosol] (Mus musculus)
Cul3 [cytosol] (Mus musculus)
CRL E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Mus musculus)
CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Mus musculus)
RBX1:CUL3:BTB [cytosol] (Mus musculus)
Cul3 [cytosol] (Mus musculus)
COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Mus musculus)
CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Mus musculus)
CRL3 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Mus musculus)
RBX1:CUL3:BTB [cytosol] (Mus musculus)
Cul3 [cytosol] (Mus musculus)
NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex (Mus musculus)
CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Mus musculus)
RBX1:CUL3:BTB [cytosol] (Mus musculus)
Cul3 [cytosol] (Mus musculus)
NEDD8-AcM-UBE2M:CRL3 E3 ubiquitin ligase :DCUN1D1,2,4,5 [cytosol] (Mus musculus)
CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Mus musculus)
RBX1:CUL3:BTB [cytosol] (Mus musculus)
Cul3 [cytosol] (Mus musculus)
Signal Transduction (Mus musculus)
MAPK family signaling cascades (Mus musculus)
MAPK1/MAPK3 signaling (Mus musculus)
RAF/MAP kinase cascade (Mus musculus)
Regulation of RAS by GAPs (Mus musculus)
KBTBD7:CUL3:RBX1 ubiquitinates NF1 (Mus musculus)
KBTBD7:CUL3:RBX1 [cytosol] (Mus musculus)
Cul3 [cytosol] (Mus musculus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Mus musculus)
RHOBTB3 ATPase cycle (Mus musculus)
RHOBTB3 binds interacting proteins at trans-Golgi network (Mus musculus)
RHOBTB3 interacting proteins [cytosol] (Mus musculus)
Cul3 [cytosol] (Mus musculus)
RHOBTB3:ATP:RHOBTB3 interacting proteins [trans-Golgi network membrane] (Mus musculus)
RHOBTB3 interacting proteins [cytosol] (Mus musculus)
Cul3 [cytosol] (Mus musculus)
Signaling by Rho GTPases (Mus musculus)
RHO GTPase cycle (Mus musculus)
RHOBTB GTPase Cycle (Mus musculus)
RHOBTB1 GTPase cycle (Mus musculus)
RHOBTB1 binds interacting proteins at the endosome membrane (Mus musculus)
RHOBTB1 interacting proteins [cytosol] (Mus musculus)
Cul3 [cytosol] (Mus musculus)
RHOBTB1:GTP:RHOBTB1 interacting proteins [endosome membrane] (Mus musculus)
RHOBTB1 interacting proteins [cytosol] (Mus musculus)
Cul3 [cytosol] (Mus musculus)
RHOBTB2 GTPase cycle (Mus musculus)
RHOBTB2 binds interacting proteins at the endosome membrane (Mus musculus)
RHOBTB2 interacting proteins [cytosol] (Mus musculus)
Cul3 [cytosol] (Mus musculus)
RHOBTB2:GTP:RHOBTB2 interacting proteins [endosome membrane] (Mus musculus)
RHOBTB2 interacting proteins [cytosol] (Mus musculus)
Cul3 [cytosol] (Mus musculus)
Signaling by WNT (Mus musculus)
TCF dependent signaling in response to WNT (Mus musculus)
Degradation of DVL (Mus musculus)
DVL is bound by the CUL3:KLHL12:RBX1 ubiquitin ligase complex (Mus musculus)
CUL3:KLHL12:RBX1 [cytosol] (Mus musculus)
Cul3 [cytosol] (Mus musculus)
DVL:CUL3:KLHL12:RBX1 [cytosol] (Mus musculus)
CUL3:KLHL12:RBX1 [cytosol] (Mus musculus)
Cul3 [cytosol] (Mus musculus)
DVL is ubiquitinated by CUL3:KLHL12:RBX1 (Mus musculus)
DVL:CUL3:KLHL12:RBX1 [cytosol] (Mus musculus)
CUL3:KLHL12:RBX1 [cytosol] (Mus musculus)
Cul3 [cytosol] (Mus musculus)
ub-DVL:CUL3:KLHL12:RBX1 [cytosol] (Mus musculus)
CUL3:KLHL12:RBX1 [cytosol] (Mus musculus)
Cul3 [cytosol] (Mus musculus)
Ubiquitinated DVL is degraded by the proteasome (Mus musculus)
CUL3:KLHL12:RBX1 [cytosol] (Mus musculus)
Cul3 [cytosol] (Mus musculus)
ub-DVL:CUL3:KLHL12:RBX1 [cytosol] (Mus musculus)
CUL3:KLHL12:RBX1 [cytosol] (Mus musculus)
Cul3 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:Q9JLV5
Gene Names
Cul3
Reference Genes
BioGPS Gene:26554 Cul3
ENSEMBL:ENSMUSG00000004364
ENSEMBL:ENSMUSG00000004364.15 Cul3
KEGG Gene (Mus musculus):26554 Cul3
Monarch:26554 Cul3
NCBI Gene:26554 Cul3
UCSC:Q9JLV5 Cul3
Reference Transcript
RefSeq:NM_001313728.1 Cul3
RefSeq:NM_016716.5 Cul3
Other Identifiers
10356001
111920_at
115360_at
1422794_at
1422795_at
1434717_at
1434718_at
1450756_s_at
164169_at
17224791
26554
4381687
4385808
4422183
4438653
4506329
4508451
4524925
4546696
4567692
4613398
4667181
4716704
4760319
4823271
4938073
4965712
5021503
5335088
5536207
92797_at
A_51_P415870
A_52_P47645
A_52_P52311
GE42736
GO:0000122
GO:0000209
GO:0000278
GO:0000902
GO:0000910
GO:0000922
GO:0001701
GO:0001831
GO:0003824
GO:0004842
GO:0005112
GO:0005515
GO:0005634
GO:0005737
GO:0005794
GO:0005813
GO:0005815
GO:0005819
GO:0005827
GO:0005856
GO:0005886
GO:0005929
GO:0006351
GO:0006355
GO:0006357
GO:0006511
GO:0006513
GO:0006888
GO:0006954
GO:0007010
GO:0007049
GO:0007059
GO:0007080
GO:0007229
GO:0007369
GO:0010467
GO:0012501
GO:0016055
GO:0016192
GO:0016477
GO:0016567
GO:0016740
GO:0017145
GO:0023052
GO:0030030
GO:0030154
GO:0030163
GO:0030332
GO:0031145
GO:0031208
GO:0031398
GO:0031461
GO:0031463
GO:0031514
GO:0031625
GO:0031648
GO:0032467
GO:0032480
GO:0035024
GO:0036126
GO:0036211
GO:0040016
GO:0042802
GO:0042995
GO:0043149
GO:0043161
GO:0043226
GO:0044346
GO:0045842
GO:0048208
GO:0048856
GO:0048870
GO:0051301
GO:0051865
GO:0061024
GO:0061630
GO:0065003
GO:0070936
GO:0071230
GO:0071630
GO:0072576
GO:0072686
GO:0098794
GO:0098978
GO:0140014
GO:0140096
GO:0140252
GO:0160072
GO:1901992
GO:1904263
ILMN_1224546
ILMN_2487814
mMC012375
mMR030802
Participates
as a member of
RHOBTB1 interacting proteins [cytosol] (Mus musculus)
RHOBTB2 interacting proteins [cytosol] (Mus musculus)
RHOBTB3 interacting proteins [cytosol] (Mus musculus)
as a component of
CUL3:KLHL12:RBX1 [cytosol] (Mus musculus)
KBTBD7:CUL3:RBX1 [cytosol] (Mus musculus)
RBX1:CUL3:BTB [cytosol] (Mus musculus)
Other forms of this molecule
Cul3 [cytosol]
Cul3 [nucleoplasm]
Inferred From
CUL3 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001300657.1
,
NP_057925.1
Ensembl
ENSMUSP00000130738
,
ENSMUSG00000004364
,
ENSMUST00000163119
PRO
Q9JLV5
MGI
1347360
PDB
1IUY
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