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E3 ligases in proteasomal degradation [cytosol]
Stable Identifier
R-MMU-976075
Type
Set [CandidateSet]
Species
Mus musculus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Immune System (Mus musculus)
Adaptive Immune System (Mus musculus)
Class I MHC mediated antigen processing & presentation (Mus musculus)
Antigen processing: Ubiquitination & Proteasome degradation (Mus musculus)
Interaction of E3 with substrate and E2-Ub complex (Mus musculus)
Ag-substrate:E3:E2:Ub [cytosol] (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
Polyubiquitination of substrate (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
E3:K48-polyubiquitinated substrate [cytosol] (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
E3:Ub:substrate [cytosol] (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
Release of E3 from polyubiquitinated substrate (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
E3:K48-polyubiquitinated substrate [cytosol] (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
Transfer of Ub from E2 to substrate and release of E2 (Mus musculus)
Ag-substrate:E3:E2:Ub [cytosol] (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
E3:Ub:substrate [cytosol] (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
Participants
members
Cul1 [cytosol] (Mus musculus)
Rnf144b [cytosol] (Mus musculus)
Rnf19b [cytosol] (Mus musculus)
Mib2 [cytosol] (Mus musculus)
Nedd4l [cytosol] (Mus musculus)
Siah1a [cytosol] (Mus musculus)
Spsb1 [cytosol] (Mus musculus)
Trip12 [cytosol] (Mus musculus)
Dtx3l [cytosol] (Mus musculus)
Rbck1 [cytosol] (Mus musculus)
Siah2 [cytosol] (Mus musculus)
Trim21 [cytosol] (Mus musculus)
Trim69 [cytosol] (Mus musculus)
Ubr2 [cytosol] (Mus musculus)
Huwe1 [cytosol] (Mus musculus)
Smurf2 [cytosol] (Mus musculus)
Trim36 [cytosol] (Mus musculus)
Wsb1 [cytosol] (Mus musculus)
SCF E3 ubiquitin ligase [cytosol] (Mus musculus)
Rnf213 [cytosol] (Mus musculus)
Hectd2 [cytosol] (Mus musculus)
Lonrf1 [cytosol] (Mus musculus)
Rbbp6 [cytosol] (Mus musculus)
Rnf19a [cytosol] (Mus musculus)
Znrf1 [cytosol] (Mus musculus)
Herc6 [cytosol] (Mus musculus)
Rnf217 [cytosol] (Mus musculus)
Rnf114 [cytosol] (Mus musculus)
Znrf2 [cytosol] (Mus musculus)
Fbxl4 [cytosol] (Mus musculus)
Rlim [cytosol] (Mus musculus)
Rnf115 [cytosol] (Mus musculus)
Unkl [cytosol] (Mus musculus)
Mylip [cytosol] (Mus musculus)
candidates
Cblb [cytosol] (Mus musculus)
Stub1 [cytosol] (Mus musculus)
Dzip3 [cytosol] (Mus musculus)
Hectd3 [cytosol] (Mus musculus)
Herc2 [cytosol] (Mus musculus)
Itch [cytosol] (Mus musculus)
Lrsam1 [cytosol] (Mus musculus)
Mgrn1 [cytosol] (Mus musculus)
Nedd4 [cytosol] (Mus musculus)
Rnf182 [cytosol] (Mus musculus)
Rnf220 [cytosol] (Mus musculus)
Rnf25 [cytosol] (Mus musculus)
Rnf6 [cytosol] (Mus musculus)
Smurf1 [cytosol] (Mus musculus)
Trim11 [cytosol] (Mus musculus)
Trim32 [cytosol] (Mus musculus)
Trim37 [cytosol] (Mus musculus)
Trim63 [cytosol] (Mus musculus)
Trim9 [cytosol] (Mus musculus)
Ubr1 [cytosol] (Mus musculus)
Gan [cytosol] (Mus musculus)
Wwp1 [cytosol] (Mus musculus)
Rchy1 [cytosol] (Mus musculus)
Spsb2 [cytosol] (Mus musculus)
Spsb4 [cytosol] (Mus musculus)
Ubox5 [cytosol] (Mus musculus)
Ube4a [cytosol] (Mus musculus)
Ube3a [cytosol] (Mus musculus)
Ube3b [cytosol] (Mus musculus)
Ube3c [cytosol] (Mus musculus)
RBX1-CUL2-EloB,C-VHL [cytosol] (Mus musculus)
RBX1:CUL3:BTB [cytosol] (Mus musculus)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Mus musculus)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Mus musculus)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Mus musculus)
RBX1:CUL7:SKP1:FBXW8:GLMN [cytosol] (Mus musculus)
APC/C E3 ligase complex [cytosol] (Mus musculus)
Ubr4 [cytosol] (Mus musculus)
Lrrc41 [cytosol] (Mus musculus)
Rnf41 [cytosol] (Mus musculus)
Pja2 [cytosol] (Mus musculus)
Rnf123 [cytosol] (Mus musculus)
Pja1 [cytosol] (Mus musculus)
Prkn [cytosol] (Mus musculus)
Rnf34 [cytosol] (Mus musculus)
Fbxo17 [cytosol] (Mus musculus)
Fbxo27 [cytosol] (Mus musculus)
Fbxo44 [cytosol] (Mus musculus)
Rnf4 [cytosol] (Mus musculus)
Arih2 [cytosol] (Mus musculus)
Rnf138 [cytosol] (Mus musculus)
Mkrn1 [cytosol] (Mus musculus)
Lrr1 [cytosol] (Mus musculus)
Rnf111 [cytosol] (Mus musculus)
Dcaf1 [cytosol] (Mus musculus)
Det1 [cytosol] (Mus musculus)
Hectd1 [cytosol] (Mus musculus)
Ltn1 [cytosol] (Mus musculus)
Rnf14 [cytosol] (Mus musculus)
Sh3rf1 [cytosol] (Mus musculus)
Traf7 [cytosol] (Mus musculus)
Trim39 [cytosol] (Mus musculus)
Trim41 [cytosol] (Mus musculus)
Trim50 [cytosol] (Mus musculus)
Trim71 [cytosol] (Mus musculus)
Ufl1 [cytosol] (Mus musculus)
Arel1 [cytosol] (Mus musculus)
Btbd1 [cytosol] (Mus musculus)
Hace1 [cytosol] (Mus musculus)
Hecw2 [cytosol] (Mus musculus)
Herc1 [cytosol] (Mus musculus)
Herc3 [cytosol] (Mus musculus)
Herc4 [cytosol] (Mus musculus)
Klhl11 [cytosol] (Mus musculus)
Lnx1 [cytosol] (Mus musculus)
Mex3c [cytosol] (Mus musculus)
Rnf126 [cytosol] (Mus musculus)
Rnf130 [cytosol] (Mus musculus)
Traip [cytosol] (Mus musculus)
Ubac1 [cytosol] (Mus musculus)
Ube3d [cytosol] (Mus musculus)
Cbll1 [cytosol] (Mus musculus)
Participant Of
hasComponent
Ag-substrate:E3:E2:Ub [cytosol]
E3:K48-polyubiquitinated substrate [cytosol]
E3:Ub:substrate [cytosol]
input
Interaction of E3 with substrate and E2-Ub complex
output
Release of E3 from polyubiquitinated substrate
Inferred From
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
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