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K33polyUb-K197,302,364-RIPK3 [cytosol]
Stable Identifier
R-MMU-9794180
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
Q9QZL0
Locations in the PathwayBrowser for interactor UniProt:Q9D2Y4
Expand all
Programmed Cell Death (Mus musculus)
Regulated Necrosis (Mus musculus)
RIPK1-mediated regulated necrosis (Mus musculus)
Regulation of necroptotic cell death (Mus musculus)
PRKN polyubiquitinates RIPK3 (Mus musculus)
K33polyUb-K197,302,364-RIPK3 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:Q9QZL0
Reference Genes
BioGPS Gene:56532
ENSEMBL:ENSMUSG00000022221
ENSEMBL:ENSMUSG00000022221.15
KEGG Gene (Mus musculus):56532
Monarch:56532
NCBI Gene:56532
UCSC:Q9QZL0
Reference Transcript
RefSeq:NM_019955.2
Other Identifiers
10420198
114018_at
1448449_at
17306906
4327283
4375265
4386256
4507608
4687355
4851867
4952766
5015618
5094511
5205975
5361504
5425578
5491383
56532
A_51_P491987
GE120337
GO:0000166
GO:0001914
GO:0002376
GO:0002819
GO:0003824
GO:0004672
GO:0004674
GO:0005515
GO:0005524
GO:0005634
GO:0005737
GO:0005829
GO:0006468
GO:0006915
GO:0007165
GO:0012501
GO:0016301
GO:0016310
GO:0016740
GO:0023052
GO:0030154
GO:0032147
GO:0032649
GO:0032991
GO:0033077
GO:0036211
GO:0038061
GO:0042802
GO:0042981
GO:0043029
GO:0043226
GO:0044877
GO:0046006
GO:0046777
GO:0048535
GO:0048536
GO:0048538
GO:0048856
GO:0048870
GO:0051607
GO:0060545
GO:0070235
GO:0070266
GO:0070301
GO:0072593
GO:0097300
GO:0097527
GO:0097528
GO:0098542
GO:0106310
GO:0140096
GO:1990000
GO:2000377
GO:2000379
GO:2000452
GO:2001244
ILMN_2750353
ILMN_2750356
mMC018919
Participates
as an output of
PRKN polyubiquitinates RIPK3 (Mus musculus)
Other forms of this molecule
phospho-p-S199,227, K48pUb-363-RIPK3 [cytosol]
OGlcNAc-T467-RIPK3 [cytosol]
RIPK3(329-518) [cytosol]
RIPK3(1-328) [cytosol]
Ub-K55,363-RIPK3 [cytosol]
phospho-p-S199,227-RIPK3 [cytosol]
RIPK3 [cytosol]
Inferred From
K33polyUb-K197,302,364-RIPK3 [cytosol]
(Homo sapiens)
Modified Residues
Name
ubiquitinylated lysine (K33polyUb [cytosol]) at 197 (in Homo sapiens)
Coordinate
197
Modification
K33polyUb [cytosol]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Name
ubiquitinylated lysine (K33polyUb [cytosol]) at 302 (in Homo sapiens)
Coordinate
302
Modification
K33polyUb [cytosol]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Name
ubiquitinylated lysine (K33polyUb [cytosol]) at 364 (in Homo sapiens)
Coordinate
364
Modification
K33polyUb [cytosol]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
NP_064339.2
Ensembl
ENSMUST00000022830
,
ENSMUSP00000022830
,
ENSMUSG00000022221
PRO
Q9QZL0
MGI
2154952
PDB
4M69
,
6JPD
,
4M66
,
6OKO
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q61160
1
Fadd [cytosol]
(R-MMU-54639)
0.802
6
UniProt:Q9D2Y4
3
phospho-K63PolyUb-K50,p-T357,S358-MLKL [cytosol]
(R-MMU-9793468)
phospho-p-T357,S358-MLKL [cytosol]
(R-MMU-5218903)
MLKL [cytosol]
(R-MMU-5218901)
0.641
3
UniProt:Q60855
14
K48polyUb-RIPK1 [cytosol]
(R-MMU-6783308)
PolyUb-RIPK1 [cytosol]
(R-MMU-6783197)
RIPK1 [cytosol]
(R-MMU-168651)
K63polyUb-RIPK1 [cytosol]
(R-MMU-937021)
phospho-p-S166-RIPK1 [cytosol]
(R-MMU-5218872)
phospho-p-S357-RIPK1 [cytosol]
(R-MMU-9819116)
phospho-p-S320-RIPK1 [cytosol]
(R-MMU-9815498)
phospho-K63,M1polyUb, p-T189-RIPK1 [cytosol]
(R-MMU-9817377)
polyUb-K377,K604,K634-RIPK1 [cytosol]
(R-MMU-9818391)
RIPK1(325-671) [cytosol]
(R-MMU-5212671)
RIPK1(1-324) [cytosol]
(R-MMU-5212664)
K63,M1polyUb-RIPK1 [cytosol]
(R-MMU-9793681)
phospho-K63,Met1polyUb-p-S25-RIPK1 [cytosol]
(R-MMU-9818793)
K48polyUb-K571,K604,K627-RIPK1 [cytosol]
(R-MMU-9796639)
0.589
4
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