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ALKAL2:(ALKAL1) [extracellular region]
Stable Identifier
R-MMU-9842597
Type
Set [CandidateSet]
Species
Mus musculus
Compartment
extracellular region
Locations in the PathwayBrowser
Expand all
Signal Transduction (Mus musculus)
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by ALK (Mus musculus)
ALK autophosphorylation (Mus musculus)
ALK dimer:ligand:type I ALK binding TKI [plasma membrane] (Mus musculus)
ligand-bound ALK dimer [plasma membrane] (Mus musculus)
ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Mus musculus)
ALKAL2:(ALKAL1) [extracellular region] (Mus musculus)
Active ALK dimer [plasma membrane] (Mus musculus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Mus musculus)
ALKAL2:(ALKAL1) [extracellular region] (Mus musculus)
ligand-bound ALK dimer [plasma membrane] (Mus musculus)
ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Mus musculus)
ALKAL2:(ALKAL1) [extracellular region] (Mus musculus)
ALK binds ALKAL ligand (Mus musculus)
ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Mus musculus)
ALKAL2:(ALKAL1) [extracellular region] (Mus musculus)
ALKAL2:(ALKAL1) [extracellular region] (Mus musculus)
Active ALK binds JAK3 (Mus musculus)
Active ALK dimer [plasma membrane] (Mus musculus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Mus musculus)
ALKAL2:(ALKAL1) [extracellular region] (Mus musculus)
Active ALK:JAK3 [plasma membrane] (Mus musculus)
Active ALK dimer [plasma membrane] (Mus musculus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Mus musculus)
ALKAL2:(ALKAL1) [extracellular region] (Mus musculus)
Active ALK binds PLCG1 (Mus musculus)
Active ALK dimer [plasma membrane] (Mus musculus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Mus musculus)
ALKAL2:(ALKAL1) [extracellular region] (Mus musculus)
Active ALK:PLCG1 [plasma membrane] (Mus musculus)
Active ALK dimer [plasma membrane] (Mus musculus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Mus musculus)
ALKAL2:(ALKAL1) [extracellular region] (Mus musculus)
Active ALK binds SHC1 (Mus musculus)
Active ALK dimer [plasma membrane] (Mus musculus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Mus musculus)
ALKAL2:(ALKAL1) [extracellular region] (Mus musculus)
Active ALK:SHC1 [plasma membrane] (Mus musculus)
Active ALK dimer [plasma membrane] (Mus musculus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Mus musculus)
ALKAL2:(ALKAL1) [extracellular region] (Mus musculus)
Active ALK dimer binds IRS1 (Mus musculus)
Active ALK dimer [plasma membrane] (Mus musculus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Mus musculus)
ALKAL2:(ALKAL1) [extracellular region] (Mus musculus)
Active ALK:IRS1 [plasma membrane] (Mus musculus)
Active ALK dimer [plasma membrane] (Mus musculus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Mus musculus)
ALKAL2:(ALKAL1) [extracellular region] (Mus musculus)
Active ALK phosphorylates IRS1 (Mus musculus)
Active ALK:IRS1 [plasma membrane] (Mus musculus)
Active ALK dimer [plasma membrane] (Mus musculus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Mus musculus)
ALKAL2:(ALKAL1) [extracellular region] (Mus musculus)
Active ALK:pY-IRS1 [plasma membrane] (Mus musculus)
Active ALK dimer [plasma membrane] (Mus musculus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Mus musculus)
ALKAL2:(ALKAL1) [extracellular region] (Mus musculus)
Active ALK phosphorylates JAK3 (Mus musculus)
Active ALK:JAK3 [plasma membrane] (Mus musculus)
Active ALK dimer [plasma membrane] (Mus musculus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Mus musculus)
ALKAL2:(ALKAL1) [extracellular region] (Mus musculus)
Active ALK:p-Y980 JAK3 [plasma membrane] (Mus musculus)
Active ALK dimer [plasma membrane] (Mus musculus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Mus musculus)
ALKAL2:(ALKAL1) [extracellular region] (Mus musculus)
Active ALK phosphorylates PLCG1 (Mus musculus)
Active ALK:PLCG1 [plasma membrane] (Mus musculus)
Active ALK dimer [plasma membrane] (Mus musculus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Mus musculus)
ALKAL2:(ALKAL1) [extracellular region] (Mus musculus)
Active ALK:p-4Y PLCG1 [plasma membrane] (Mus musculus)
Active ALK dimer [plasma membrane] (Mus musculus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Mus musculus)
ALKAL2:(ALKAL1) [extracellular region] (Mus musculus)
Active ALK phosphorylates SHC1 (Mus musculus)
Active ALK:SHC1 [plasma membrane] (Mus musculus)
Active ALK dimer [plasma membrane] (Mus musculus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Mus musculus)
ALKAL2:(ALKAL1) [extracellular region] (Mus musculus)
Active ALK:p-3Y SHC1 [plasma membrane] (Mus musculus)
Active ALK dimer [plasma membrane] (Mus musculus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Mus musculus)
ALKAL2:(ALKAL1) [extracellular region] (Mus musculus)
Active ALK recruits PI3K (Mus musculus)
Active ALK dimer [plasma membrane] (Mus musculus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Mus musculus)
ALKAL2:(ALKAL1) [extracellular region] (Mus musculus)
Active ALK:PI3K [plasma membrane] (Mus musculus)
Active ALK dimer [plasma membrane] (Mus musculus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Mus musculus)
ALKAL2:(ALKAL1) [extracellular region] (Mus musculus)
Liganded-ALK dimer binds type I ALK-binding TKIs (Mus musculus)
ALK dimer:ligand:type I ALK binding TKI [plasma membrane] (Mus musculus)
ligand-bound ALK dimer [plasma membrane] (Mus musculus)
ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Mus musculus)
ALKAL2:(ALKAL1) [extracellular region] (Mus musculus)
ligand-bound ALK dimer [plasma membrane] (Mus musculus)
ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Mus musculus)
ALKAL2:(ALKAL1) [extracellular region] (Mus musculus)
PI3K synthesizes PIP3 downstream of ALK (Mus musculus)
Active ALK:PI3K [plasma membrane] (Mus musculus)
Active ALK dimer [plasma membrane] (Mus musculus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Mus musculus)
ALKAL2:(ALKAL1) [extracellular region] (Mus musculus)
PTPN6 dephosphorylates JAK3 (Mus musculus)
Active ALK:JAK3 [plasma membrane] (Mus musculus)
Active ALK dimer [plasma membrane] (Mus musculus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Mus musculus)
ALKAL2:(ALKAL1) [extracellular region] (Mus musculus)
Active ALK:p-Y980 JAK3 [plasma membrane] (Mus musculus)
Active ALK dimer [plasma membrane] (Mus musculus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Mus musculus)
ALKAL2:(ALKAL1) [extracellular region] (Mus musculus)
STAT3 is phosphorylated downstream of active ALK (Mus musculus)
Active ALK dimer [plasma membrane] (Mus musculus)
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Mus musculus)
ALKAL2:(ALKAL1) [extracellular region] (Mus musculus)
Participants
members
ALKAL2 dimer [extracellular region]
(Mus musculus)
candidates
Alkal1 [extracellular region]
(Mus musculus)
Participates
as a component of
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Mus musculus)
ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] (Mus musculus)
as an input of
ALK binds ALKAL ligand (Mus musculus)
Inferred From
ALKAL2:(ALKAL1) [extracellular region]
(Homo sapiens)
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