Glucanotrehalose is hydrolyzed to 1,4-alpha-glucan and trehalose

Stable Identifier
R-MTU-868657
Type
Reaction [transition]
Species
Mycobacterium tuberculosis
Compartment
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Glucanotrehalose is hydrolyzed to 1,4-alpha-glucan and trehalose
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
From the glucanotrehalose, the enzyme TreZ cleaves one molecule of trehalose, leaving a linear glucan that is two sugars shorter than before. This is the rate-limiting step in the TreYZ pathway of trehalose biosynthesis (De Smet et al, 2000).
Literature References
PubMed ID Title Journal Year
10658666 Three pathways for trehalose biosynthesis in mycobacteria

De Smet, KA, Weston, A, Brown, IN, Young, DB, Robertson, BD

Microbiology 2000
Participants
Input
Output
Participates
as an event of
Catalyst Activity

4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity of TreZ [cytosol]

Physical Entity
TreZ [cytosol] (Mycobacterium tuberculosis)
Activity
4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity (GO:0033942)
Authored
Stephan, R  (2010-05-29)
Reviewed
Warner, D  (2010-11-25)
Created
Stephan, R  (2010-06-02)
Cite Us!