Smad7 binds SMURF1

Stable Identifier
R-NUL-2169004
Type
Reaction [binding]
Species
Homo sapiens
Compartment
General
SVG |   | PPTX  | SBGN
Smad7 binds SMURF1

Recombinant mouse Smad7 exogenously expressed in COS7 or HEK293 cells binds exogenously expressed recombinant human SMURF1 (Ebisawa et al. 2001, Tajima et al. 2003).

Literature References
PubMed ID Title Journal Year
12519765 Chromosomal region maintenance 1 (CRM1)-dependent nuclear export of Smad ubiquitin regulatory factor 1 (Smurf1) is essential for negative regulation of transforming growth factor-beta signaling by Smad7

Tajima, Y, Goto, K, Yoshida, M, Shinomiya, K, Sekimoto, T, Yoneda, Y, Miyazono, K, Imamura, T

J Biol Chem 2003
11278251 Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation

Ebisawa, T, Fukuchi, M, Murakami, G, Chiba, T, Tanaka, K, Imamura, T, Miyazono, K

J Biol Chem 2001
Participants
Orthologous Events
Authored
Reviewed
Created