Translocation of Smad7:NEDD4L complex to the cytosol

Stable Identifier
R-NUL-2176428
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol, nucleoplasm
ReviewStatus
5/5
General
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PNG
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 | PPTX  | SBGN
Translocation of Smad7:NEDD4L complex to the cytosol
Co-transfection of recombinant mouse Smad7 and recombinant human NEDD4L in HepG2 cells, COS7 cells of HEK293 cells, results in the mainly cytoplasmic localization of Smad7. In the absensce of NEDD4L, Smad7 is predominantly found in the nucleus (Kuratomi et al. 2005).
Literature References
Participants
Input
Output
Orthologous Events
SMAD7:NEDD4L complex translocates to the cytosol (Homo sapiens)
Authored
Orlic-Milacic, M  (2012-04-05)
Reviewed
Huang, T  (2012-05-14)
Created
Orlic-Milacic, M  (2012-04-02)
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