Rnf111 binds SKI/SKIL in complex with SMAD2/3:SMAD4 upon TGF-beta stimulation

Stable Identifier
R-NUL-2186736
Type
Reaction
Species
Homo sapiens
Compartment
General
SVG |   | PPTX  | SBGN
Rnf111 binds SKI/SKIL in complex with SMAD2/3:SMAD4 upon TGF-beta stimulation

Recombinant mouse Rnf111 (Arkadia) binds to the complex of endogenous human Smad2/3 and recombinant human SKI/SKIL in response to TGF-beta or activin stimulation (Levy et al. 2007).

Literature References
PubMed ID Title Journal Year
17591695 Arkadia activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradation

Levy, L, Howell, M, Das, D, Harkin, S, Episkopou, V, Hill, CS

Mol Cell Biol 2007
Participants
Orthologous Events
Authored
Reviewed
Created