Reactome will be unavailable due to host maintenance from Friday, April 27 at 6pm to Sunday, April 29 at 11:55pm.

During the outage, you may wish to use our mirror site at reactome.ncpsb.org.

Osteopontin binds Integrins alphaVbeta1, 3, 5

Stable Identifier
R-NUL-2752124
Type
Reaction
Species
Homo sapiens
Compartment
Summation

Osteopontin (SPP1) is a highly phosphorylated sialoprotein that is a prominent component of the mineralized extracellular matrices of bones and teeth. It binds multiple integrins including alphaVbeta3, alphaVbeta1 and alphaVbeta5 (Liaw et al. 1995).

Participants
Orthologous Events