Reactome: A Curated Pathway Database

Osteopontin binds Integrins alphaVbeta1, 3, 5

Stable Identifier
R-NUL-2752124
Type
Reaction
Species
Homo sapiens
Compartment
Summation

Osteopontin (SPP1) is a highly phosphorylated sialoprotein that is a prominent component of the mineralized extracellular matrices of bones and teeth. It binds multiple integrins including alphaVbeta3, alphaVbeta1 and alphaVbeta5 (Liaw et al. 1995).

Literature References
Participants
Orthologous Events