AKT phosphorylates Bad

Stable Identifier
R-NUL-3139045
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
AKT phosphorylates Bad
Recombinant human activated AKT proteins phosphorylate recombinant mouse Bad at serine 136 (Datta et al. 1997, del Peso et al. 1997).
Literature References
PubMed ID Title Journal Year
9346240 Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

Fu, H, Tao, X, Masters, S, Dudek, H, Gotoh, Y, Datta, SR, Greenberg, ME

Cell 1997
9381178 Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

Page, CP, Nunez, G, Gonzalez-Garcia, M, Herrera, R, del Peso, L

Science 1997
Participants
Input
Output
Catalyst Activity

protein serine/threonine kinase activity of p-T,p-S-AKT [cytosol]

Physical Entity
p-T,p-S-AKT [cytosol] (Homo sapiens)
Activity
protein serine/threonine kinase activity (GO:0004674)
Orthologous Events
AKT phosphorylates BAD (Homo sapiens)
Authored
Orlic-Milacic, M  (2013-02-13)
Reviewed
D'Eustachio, P  (2013-02-13)
Created
Orlic-Milacic, M  (2013-02-13)
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