Collagen type IV binds integrin alpha2beta1, alpha1beta1

Stable Identifier
R-NUL-4084922
Type
Reaction
Species
Homo sapiens
Compartment
Summation

Integrin alpha2beta1 and alpha1beta1 both bind collagen types I-IV (Tulla et al. 2001). Integrin alpha1beta1 binds to collagen type IV and VI with higher affinity than to types I-III, whereas alpha2beta1 has a higher affinity for collagen types I-III than for type IV (Tulla et al. 2001).

Literature References
PubMed ID Title Journal Year
11572855 Selective binding of collagen subtypes by integrin alpha 1I, alpha 2I, and alpha 10I domains

Tulla, M, Pentikäinen, OT, Viitasalo, T, Käpylä, J, Impola, U, Nykvist, P, Nissinen, L, Johnson, MS, Heino, J

J. Biol. Chem. 2001
Participants
Orthologous Events
Authored
Reviewed